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DTIL - Precision BioSciences Announces Oral Presentation at the 2025 Muscular Dystrophy Association (MDA) Clinical & Scientific Conference


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  • February, 24 2025 07:01 AM
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MWN AI Summary *

Precision BioSciences, Inc. (Nasdaq: DTIL), a clinical-stage gene editing company, is set to present groundbreaking preclinical data from its PBGENE-DMD program aimed at treating Duchenne muscular dystrophy (DMD) at the 2025 Muscular Dystrophy Association (MDA) Clinical & Scientific Conference. Scheduled for March 19, 2025, at 8:00 AM CT, the oral presentation is titled "ARCUS-Mediated Excision of Exons 45-55 Leads to Functional Del45-55 Dystrophin and Restoration of Skeletal Muscle-Function for the Treatment of DMD." The abstract for this presentation is publicly accessible on the MDA website, indicating high transparency and engagement with the scientific community.

Precision BioSciences utilizes its proprietary ARCUS® platform, which employs unique genome editing techniques to address genetic disorders where conventional treatments fall short. The ARCUS technology is celebrated for its precision and efficiency in making specific genetic modifications through methods like gene insertion, elimination, and excision. This platform allows the company to effectively deliver durable, meaningful therapeutic outcomes, especially crucial for conditions like DMD, which severely impacts muscle strength and function.

The PBGENE-DMD program leverages the ARCUS platform to excise defective gene segments, promoting the production of a functional dystrophin protein, which is essential for muscle functionality. The company's commitment to developing gene editing therapies opens new avenues for treating genetic and infectious diseases, thereby striving to provide "lasting cures" for patients with limited options.

For more information about Precision BioSciences and their innovative approaches to gene editing, further details can be found on their website at www.precisionbiosciences.com.

MWN AI Analysis *

Precision BioSciences, Inc. (Nasdaq: DTIL) recently announced it will present groundbreaking preclinical data concerning its PBGENE-DMD program at the 2025 MDA Clinical & Scientific Conference. This program explores gene editing therapies aimed at treating Duchenne muscular dystrophy (DMD). As the presentation approaches on March 19, 2025, investors should carefully consider the implications of this development for the company and its stock.

The innovative ARCUS® gene editing platform distinguishes Precision BioSciences from its competitors by offering a unique approach to genome editing characterized by its smaller size and simpler cutting mechanism. The oral presentation will cover crucial data showing how the ARCUS platform can excise exons 45-55 in the dystrophin gene, essential for muscle function restoration in DMD patients. If the data presented demonstrates significant efficacy and safety, it could position Precision BioSciences as a leader in the gene therapy space.

Investors should note that advancements in clinical trials and presentations at significant scientific conferences often generate considerable market interest and can lead to stock price appreciation. Therefore, closely monitoring the response to the presentation and any resulting commentary from analysts and industry experts will be vital. Increased visibility in the scientific community can attract potential partnerships or further investment, bolstering the company’s growth trajectory.

However, it is crucial to remain aware of the inherent risks associated with clinical-stage biotech investments. Clinical trials can encounter setbacks, and regulatory approval remains uncertain. Market volatility surrounding the presentation could create short-term trading opportunities; thus, investors might consider strategic entry points or hedging strategies.

In summary, while Precision BioSciences holds considerable promise in the gene editing field, investors should weigh the potential upside against the inherent risks of clinical trials and market speculation leading up to the March 2025 conference.

* MWN AI Summary and Analysis is based on asking OpenAI to summarize and analyze this news release.


Precision BioSciences, Inc. (Nasdaq: DTIL), a clinical stage gene editing company utilizing its novel proprietary ARCUS® platform to develop in vivo gene editing therapies, including gene elimination, gene insertion, and gene excision programs, today announced that the company will present preclinical data from the PBGENE-DMD program for the treatment of Duchenne muscular dystrophy (DMD) during an oral presentation at the 2025 Muscular Dystrophy Association (MDA) Clinical & Scientific Conference being held March 16-19, 2025.

Presentation Details:

Title: ARCUS-Mediated Excision of Exons 45-55 Leads to Functional Del45-55 Dystrophin and Restoration of Skeletal Muscle-Function for the Treatment of DMD
Date and Time: Wednesday, March 19, 2025, 8:00 AM CT

The abstract is now publicly accessible through the MDA website here .

About Precision BioSciences, Inc.

Precision BioSciences, Inc. is a clinical stage gene editing company dedicated to improving life (DTIL) with its novel and proprietary ARCUS® genome editing platform that differs from other technologies in the way it cuts, its smaller size, and its simpler structure. Key capabilities and differentiating characteristics may enable ARCUS nucleases to drive more intended, defined therapeutic outcomes. Using ARCUS, the Company’s pipeline is comprised of in vivo gene editing candidates designed to deliver lasting cures for the broadest range of genetic and infectious diseases where no adequate treatments exist. For more information about Precision BioSciences, please visit www.precisionbiosciences.com .

The ARCUS® platform is being used to develop in vivo gene editing therapies for sophisticated gene edits, including gene insertion (inserting DNA into gene to cause expression/add function), elimination (removing a genome e.g. viral DNA or mutant mitochondrial DNA), and excision (removing a large portion of a defective gene by delivering two ARCUS nucleases in a single AAV such as in the DMD program for oral presentation at the MDA Clinical & Scientific Conference).

View source version on businesswire.com: https://www.businesswire.com/news/home/20250224445387/en/

Investor and Media Contact:
Naresh Tanna
Vice President of Investor Relations
naresh.tanna@precisionbiosciences.com


MWN AI FAQ **

How does Precision BioSciences Inc. DTIL plan to leverage its ARCUS® platform in future clinical trials beyond the PBGENE-DMD program?

Precision BioSciences Inc. plans to leverage its ARCUS® platform in future clinical trials by expanding its applications in gene editing for other genetic disorders and potential therapeutic areas, enhancing precision and efficiency in therapeutic development.

What are the expected timelines for the regulatory review and potential market introduction of therapies developed using Precision BioSciences Inc. DTIL's ARCUS technology?

The expected timelines for regulatory review and potential market introduction of therapies using Precision BioSciences Inc.'s ARCUS technology typically range from 1 to 5 years, depending on the specific therapy, regulatory pathways, and trial outcomes.

Can you provide insights into the preclinical results related to safety and efficacy observed in the PBGENE-DMD program from Precision BioSciences Inc. DTIL?

The preclinical results of the PBGENE-DMD program from Precision BioSciences Inc. DTIL demonstrate promising safety and efficacy profiles, showing potential for advancing gene editing solutions in treating Duchenne Muscular Dystrophy.

What competitive advantages does Precision BioSciences Inc. DTIL believe the ARCUS platform offers compared to other gene editing technologies currently in development?

Precision BioSciences Inc. believes the ARCUS platform offers a unique competitive advantage through its high precision, reduced off-target effects, and the ability to seamlessly edit larger genomic sequences compared to other gene editing technologies in development.

** MWN AI Questions are based on asking OpenAI to ask and answer four questions about this news release.

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