INAB - IN8bio Strengthens Intellectual Property Portfolio with Newly Granted Global Patents | Benzinga
- Newly granted patents expand the use of the DeltEx Drug Resistant Immunotherapy (DRI) platform to encompass Chimeric Antigen Receptor T-cell (CAR-T) and checkpoint inhibitors (CPIs).
- Broadens IN8bio's foundational intellectual property (IP) for its proprietary DeltEx DRI platform which covers the use of any genetic modification that conveys chemotherapy resistance in gamma-delta T cells, as well as natural killer (NK) cells.
- IN8bio now holds 19 total granted U.S. and international patents, and numerous pending patent applications.
NEW YORK, Sept. 19, 2023 (GLOBE NEWSWIRE) -- IN8bio, Inc. (NASDAQ:INAB), a leading clinical-stage biopharmaceutical company focused on innovative gamma-delta T cell therapies, today announced significant updates to its foundational IP portfolio. The company was recently granted patents around the world that cover use of the combination of its proprietary DeltEx DRI platform with CAR-T and CPI's.
IN8bio's DRI platform uses genetic engineering to empower gamma-delta T cells with resistance to the killing effects of chemotherapy enabling them to be more effective at killing cancer cells. This innovative approach allows synergistic combinations with standard-of-care chemotherapy regimens to strengthen the immune response and broadly eliminate cancer cells. The technology covered by the newly granted patents enhance the therapeutic potential of DRI cells by enabling their integration with CAR-T technology and CPIs, thereby bolstering the potential effectiveness of the drug therapy against solid tumor cancers.
William Ho, CEO and co-founder of IN8bio, stated, "Establishing a robust IP foundation is pivotal to the successful growth and expansion of our business. Our proprietary DRI technology, which generates chemotherapy-resistant cells, allows for the synergistic combination with front-line chemotherapies to break down barriers preventing a robust immune response. Our technology, supported by these newly granted patents opens avenues for expanding the application of these cells in conjunction with CAR-T technologies and checkpoint inhibitors to advance the fight against cancer. By harnessing these cells, we can bring cell therapy to the forefront of treatment options and offer new hope towards realizing our mission of achieving ‘Cancer Zero,' our goal of pursuing the safe eradication of all tumor cells in patients fighting cancer."
IN8bio's DRI platform has enabled a deep pipeline of product candidates. The Company ...