NVS - Novartis' Oral Drug For Chronic Skin Disease Candidate Shows Efficacy Long-term Safety | Benzinga
On Friday, Novartis AG (NYSE:NVS) released new data that confirm the long-term efficacy and safety of remibrutinib, a highly selective Bruton's tyrosine kinase (BTK) inhibitor, in chronic spontaneous urticaria (CSU).
CSU is a common and distressing skin condition that causes red, raised, itchy, and sometimes painful hives or wheals (raised rash or patches) on the skin with no known obvious trigger.
In Phase 3 studies, REMIX-1 and REMIX-2, remibrutinib treatment showed significant early symptom improvement, sustained up to Week 52, in patients with CSU who remained symptomatic despite second-generation H1-antihistamine use.
New long-term Phase III REMIX-1 and REMIX-2 data assessed at Week 52 show:
- Significant improvements with remibrutinib versus placebo, ...