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OTSKF - Otsuka files Japan application for difamilast in atopic dermatitis
Otsuka Holdings Co. Ltd.
Otsuka Pharmaceutical (OTSKF) submitted a marketing application to the Pharmaceuticals and Medical Devices Agency in Japan, seeking approval for difamilast (OPA-15406), a phosphodiesterase 4 (PDE4) inhibitor in patients with atopic dermatitis.Otsuka entered into a licensing agreement with Medimetriks in 2016 which granted Medimetriks development, marketing, and manufacturing rights for difamilast in the U.S.