CFRX - ContraFect to Present at the ASM/ESCMID Joint Conference on Drug Development | Benzinga
YONKERS, New York, Sept. 19, 2023 (GLOBE NEWSWIRE) -- ContraFect Corporation (NASDAQ:CFRX), a clinical-stage biotechnology company focused on the discovery and development of direct lytic agents (DLAs), including lysins and amurin peptides, today announces that Jane Ambler, Ph.D., the Company's Vice President of Clinical Microbiology, will be presenting at the ASM/ESCMID Joint Conference on Drug Development to Meet the Challenge of Antimicrobial Resistance, which will be held in Boston, MA from September 19-22, 2023.
Dr. Ambler's presentation will review the current standards for antimicrobial susceptibility testing (AST) for the determination of antibacterial activity of therapeutic agents and the implications for clinical development. She will highlight and discuss various antibiotics in current use and several investigational agents that require a modified AST method, such as the Company's DLAs. Review and approval of new AST methods by standards development organizations, such as the Clinical and Laboratory Standards Institute (CLSI), is essential. The methodology for susceptibility testing of the Company's anti-staphylococcal lysin, exebacase, will be described as an illustrative example of a modified AST method recently approved by the CLSI in order to assess the susceptibility of clinical trial isolates in the Company's Phase 1b/2 study of exebacase currently being conducted in France in patients with chronic prosthetic joint infections (PJI) of the knee.
Presentation Details:
| Presentation Title: |
| Impact of Different Testing Methodologies on Clinical Development |
| Time and Date: |
| Wednesday, September 20, 2023, 9:45 am ET |
The Company will be presenting two posters describing the initial development of the exebacase MIC method for testing Staphylococci other than Staphylococcus aureus (SoSA) and method verification studies performed to evaluate test performance. These data together with exebacase MIC data of contemporary SoSA isolates generated by testing clinical isolates collected as part of the US SENTRY surveillance program led to the recent approval by CLSI.