HCWB - HCW Biologics Participating at H.C. Wainwright 25th Annual Global Investment Conference in New York on September 11 – 13 2023 | Benzinga
MIRAMAR, Fla., Sept. 06, 2023 (GLOBE NEWSWIRE) -- HCW Biologics Inc. (the "Company" or "HCW Biologics") (NASDAQ:HCWB), a clinical-stage biopharmaceutical company focused on discovering and developing novel immunotherapies to lengthen healthspan by disrupting the link between inflammation and age-related diseases, will participate in the H.C. Wainwright 25th Annual Global Investment Conference in New York City. On September 12, 2023, the Company will be meeting individual investors in person at the conference venue, the Lotte New York Palace Hotel in New York. In addition, a pre-recorded, virtual Company update will be available on demand beginning at 7:00 a.m. EDT on September 11, 2023 for all who register for the conference.
The update on clinical development will include a Phase 1 clinical trial to evaluate HCW9218 in solid tumors, sponsored by The Masonic Cancer Center, University of Minnesota ("UMN"). UMN is now dosing patients at the highest dose level. Due to clinical protocol requirements, dosing of the remaining patients is expected to take place in the next 3 to 6 months. The trial participants include patients with refractory/chemo-resistant ovarian cancer and colorectal cancer. There has been no dose-limiting toxicity observed in this study.
The Principal Investigator of the UMN study is Melissa A. Geller, M.D., M.S., Professor and Division Director of Gynecologic Oncology in the Department of Obstetrics, Gynecology and Women's Health at the University of Minnesota. Dr. Geller stated, "Our team is very excited to bring this clinical trial to patients who have recurrent cancer. With the ease of a subcutaneous injection, this innovative immunotherapeutic can stimulate the immune system while at the same time inhibiting proteins that cause immunosuppression. This unique combination could provide cancer patients with a novel immune-based therapy when previous treatments have failed."
"HCW9218 may define a new category of cancer treatment through modifying factors related to drug resistance and disease recurrence. In our clinical trial, we have conducted correlative studies to evaluate this potential. We look forward to presenting our findings at a major industry conference in the fall," noted Jeffrey A. Miller, M.D., Deputy Director of the Masonic Cancer Center, and Co-Principal Investigator for the UMN study.
In a second ongoing clinical study, a Company-sponsored Phase 1b/2 clinical trial to evaluate HCW9218 in advanced pancreatic cancer, the Company expects this study to be completed in the first half of 2024. There has been no dose-limiting toxicity observed in this study. This is a multi-center trial, led by the Center for Cancer Research at the National Cancer Institute ("NCI"). Dr. Christine Camp Alewine, M.D., Ph.D., is the principal investigator for the NCI clinical site. She ...