PRFX - PainReform Selected for Poster Presentation at the 13th Congress of the European Pain Federation in Budapest Hungary | Benzinga
TEL AVIV, Israel, Sept. 07, 2023 (GLOBE NEWSWIRE) -- PainReform Ltd. (NASDAQ:PRFX) ("PainReform" or the "Company"), a clinical-stage specialty pharmaceutical company focused on the reformulation of established therapeutics, today announced that Company has been selected for a poster presentation, titled "Pharmacokinetics and Safety Profiles of PRF-110 in Subjects Following Bunionectomy Surgery," at the upcoming 13th Congress of the European Pain Federation (EFIC) being held September 20-22, 2023 at the HUNGEXPO Exhibition Centre in Budapest, Hungary. The poster will be presented by Professor Eli Hazum, Chief Technology Officer of PainReform, on September 20, 2023. The poster will be available on the EFIC website after the meeting.
The poster presentation will provide further details regarding the positive safety and pharmacokinetic (PK) data from the Company's first part of its two-part Phase 3 clinical trial of PRF-110, which enrolled 15 bunionectomy patients at two clinical sites in Texas. PRF-110 was administrated intra-operatively to validate the formulation's safety and confirm optimal product instillation in the surgical wound. PRF 110 was well tolerated, all adverse events (AEs) were mild, and no serious adverse events (SAEs) were observed.
The Phase 3 trial is a randomized, double-blind, placebo and active-controlled, multicenter study to evaluate the analgesic efficacy and safety of intra-operative administration of PRF-110 following unilateral bunionectomy. PRF-110 is an oil-based, viscous, clear solution that is deposited directly into the surgical wound bed before closure to provide localized and extended postoperative analgesia. The upcoming second part of the trial will be a double-blind study, randomizing approximately 400 patients at seven clinical sites in the U.S. and measuring pain reduction by PRF-110 over 72 hours compared with placebo and plain ropivacaine.
Ilan Hadar, Chief Executive Officer of PainReform, stated, "We are honored to announce the acceptance of our poster for presentation at the highly prestigious EFIC Congress, detailing the results from the first part of our Phase 3 clinical trial. The analyses of PRF-110 indicate that ...