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CCXI - Achillion Pharmaceuticals: The Promise Of Alternative Pathway Inhibition
ChemoCentryx Inc.
I’ve been following Achillion Pharmaceuticals (ACHN) for quite some time, but became more interested after the company reported positive results of its factor D inhibitor ACH-4471 in two rare diseases – PNH and C3G.
The problem with PNH is that the results aren’t good enough for the drug to effectively compete with a heavily entrenched drug – Alexion’s (ALXN) Soliris. The data of ACH-4471 in combination with Soliris have produced promising results, but there are questions there about pricing of the combination since Soliris is one of the most expensive drugs