ALRN - Aileron begins dosing in phase 1b trial of ALRN-6924 to prevent toxicities due to chemotherapy
Aileron Therapeutics (NASDAQ:ALRN) said it treated the first patients in a phase 1b trial of ALRN-6924 to prevent chemotherapy induced toxicities. The Boston-based company is evaluating ALRN-6924 for preventing chemotherapy-induced neutropenia, other bone marrow toxicities, and toxicities outside of the bone marrow in patients with p53-mutated breast cancer being treated with chemotherapies, doxorubicin plus cyclophosphamide and docetaxel (AC+D). Neutropenia is a condition when the body has fewer neutrophils, type of white blood cells. The company expects initial interim results in Q4 2022.
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Aileron begins dosing in phase 1b trial of ALRN-6924 to prevent toxicities due to chemotherapy