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Shares of Cortexyme, Inc. plunged 35% on the news that the FDA had placed its pivotal Alzheimer’s Phase 2/3 trial on a partial clinical hold due to liver issues.
The same therapy (atuzaginstat) is set to enter a Phase 2 trial for Parkinson’s disease in 3Q21.
With a unique approach to Alzheimer’s disease, data still due from the critical part of its pivotal trial in 4Q21, and insider buying, Cortexyme merited a further look.