DNLI - Denali Therapeutics: 2021 Was Mostly Bad Luck And Trouble February, 25 2022 09:14 AM Denali Therapeutics Inc. Denali stock fell from its heights to less than half of its earlier self. A clinical hold, unsatisfactory data, etc. are to blame. While they are doing good science and are flush with cash, validation will take time. For further details see: Denali Therapeutics: 2021 Was Mostly Bad Luck And Trouble