CNSP - Dog Study May Offer Insight into How Gliomas Impact the Immune System
A recently conducted study has found that in comparison with low-grade gliomas, high-grade gliomas in canines contain more immune cells linked to suppressing immune response. The study adds to evidence suggesting that these tumors may recruit immune cells which assist with immunosuppression. Its findings may be useful in the development of future glioma treatments for both dogs and humans.
Gliomas are caused by support cells known as glial cells, which mutate and become cancerous. These cells are usually located throughout the spinal cord and brain. In canines, gliomas make up nearly 35% of all intracranial cancers and are the second most common tumor type in the central nervous system. The average rate of survival for dogs with gliomas who undergo radiation therapy ranges between 9 to 14 months, which is akin to the 14-month rate of survival for humans who undergo chemotherapy, radiation and surgery as part...
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