RPTX - Dosing underway in Repare Therapeutics' Phase 1 trial of RP-6306 in solid tumors
Repare Therapeutics (RPTX -0.3%) announces the first patient has been dosed in its Phase 1 clinical trial of RP-6306, in combination with gemcitabine for the treatment of molecularly selected advanced solid tumors (the MAGNETIC trial). MAGNETIC will assess the safety and tolerability of RP-6306 in combination with gemcitabine, and will enroll ~104 patients with tumors harboring genomic alterations. This multicenter Phase 1 study aims to determine the maximum tolerated dose, identify a recommended phase 2 dose and preferred schedule, and assess preliminary anti-tumor activity. Further updates on RP-6306 are anticipated later in 2022.
For further details see:
Dosing underway in Repare Therapeutics' Phase 1 trial of RP-6306 in solid tumors