AXGT - Gene Therapy Series 2: Delivery Systems In Gene Therapy Including Viral Vectors
Continuing with the series of articles on gene therapy, this article will discuss the various delivery methods for gene therapies with a focus on viral vectors.
What is transgene?
A transgene is a new therapeutic DNA segment that is to be inserted into the host cell. In addition to the gene needed to make the desired protein, the transgene sequence also contains few other non-coding regions, for example, the enhancer, promoter, and intron.
(An example of a transgene)
Human cells are surrounded by a protective barrier and therefore, getting the transgene containing the normal sequence