KURA - Kura Oncology teams up with Novartis for head and neck squamous cell carcinoma study
Kura Oncology (KURA) announces a clinical collaboration with Novartis (NVS) to evaluate the combination of tipifarnib and alpelisib in patients with head and neck squamous cell carcinoma ((HNSCC)) whose tumors have HRAS overexpression or PIK3CA mutation and/or amplification.The Phase 1/2 KURRENT trial is a biomarker-defined cohort study designed to evaluate the safety, determine the recommended combination dosing and assess early anti-tumor activity of the drug combination for the treatment of HNSCC patients.Under the collaboration, Kura maintains global development and commercial rights to tipifarnib.
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Kura Oncology teams up with Novartis for head and neck squamous cell carcinoma study