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One way to look at the immuno-oncology landscape over the last few years has been to think of it as The Quest for Synergy.
And while there are indeed plenty of indications and plenty of targets yet to be explored, with plenty of antibodies for each, etc., what we've been seeing are some of the best shots, the most-likely-to-succeeds, coming up short.
Roche is going ahead with their other TIGIT trials, as well they should, because you really never do know.