MRTX - Why Shares of Mirati Therapeutics Fell Wednesday
Shares of Mirati Therapeutics (NASDAQ: MRTX) slumped more than 28% on Wednesday. The clinical-stage biotech specializes in antibody therapies to treat cancer.
The stock has been falling all week. On Monday, the company released early phase 2 data on Adagrasib to treat non-small cell lung cancer (NSCLC), along with Keytruda, which is sold by Merck (NYSE: MRK) . There are several factors at work here. On Wednesday, Mirati presented the data from its Krystal 7 and Krystal 1 trials with Adagrasib, at the 2022 ESMO Immuno-Oncology Annual Congress. The data was unimpressive for analysts and investors, who might be thinking the drug's objective response rate to NSCLC as a first-line combination therapy to treat advanced cases of the disease isn't enough to distinguish Adagrasib from the current standard of care of Keytruda and chemotherapy.
The other concern is that the drug has a Prescription Drug User Fee Action date of Dec. 14 with the Food and Drug Administration. It is possible word has leaked out that Adagrasib's approval will be denied or delayed.
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Why Shares of Mirati Therapeutics Fell Wednesday