Bicycle Therapeutics, PLC (NASDAQ: BCYC) was featured in a recent equity research report published by ROTH Capital Partners LLC. The report reads, “Bicycle today announced a new strategic collaboration agreement with Genentech to discover, develop, and commercialize novel Bicycle-based immuno-oncology (IO) therapies. Bicycle will receive a $30 million upfront payment as part of this early discovery collaboration with the possibility to receive a total of $1.7 billion in aggregate payments based on discovery, development, regulatory, and commercial milestones. See the full report for details.”
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About Bicycle Therapeutics, PLC
Bicycle Therapeutics is a clinical-stage biopharmaceutical company developing a novel class of medicines, referred to as Bicycles®, for diseases that are underserved by existing therapeutics. Bicycles are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. This constraint facilitates target binding with high affinity and selectivity, making Bicycles attractive candidates for drug development. Bicycle’s lead product candidate, BT1718, a Bicycle Toxin Conjugate (BTC) that targets MT1-MMP, is being investigated in an ongoing Phase I/IIa clinical trial in collaboration with the Centre for Drug Development of Cancer Research UK. Bicycle is also evaluating BT5528, a second-generation BTC targeting EphA2, in a Company-sponsored Phase I/II study. Bicycle is headquartered in Cambridge, UK with many key functions and members of its leadership team located in Lexington, MA. For more information, visit www.bicycletherapeutics.com.
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