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SeaStar Medical to Present at Upcoming NobleCon21 Investor Conference

MWN-AI** Summary

SeaStar Medical Holding Corporation (Nasdaq: ICU) has announced that CEO Eric Schlorff will present at the upcoming NobleCon21, the Twenty-First Annual Emerging Growth Equity Conference hosted by Noble Capital Markets. The event will take place on December 3, 2025, at Florida Atlantic University in Boca Raton, Florida. During his presentation, Schlorff aims to provide insights into the company's innovative approaches to treating critically ill patients facing organ failure. Investors and interested guests are invited to attend, with registration available using the code ICUNOBLECON.

SeaStar Medical, primarily focused on transforming the landscape of critical care medicine, has made substantial progress with its QUELIMMUNE (SCD-PED) therapy. This groundbreaking product, developed from the proprietary Selective Cytopheretic Device (SCD) technology, received FDA approval in 2024. It stands out as the only FDA-approved treatment targeting life-threatening acute kidney injury (AKI) due to sepsis in critically ill pediatric patients, marking a significant advancement in addressing this ultra-rare medical condition.

The company has also gained Breakthrough Device Designation from the FDA for six therapeutic indications, providing a favorable pathway for future approvals and reimbursement considerations. Currently, SeaStar Medical is conducting a pivotal trial of its SCD therapy for adult patients with AKI who require continuous renal replacement therapy (CRRT)—a serious health issue that affects over 200,000 adults in the U.S. annually and lacks effective treatment options.

A replay of Schlorff's presentation will be available on the company's website on December 4, 2025, for those unable to attend live. For further information, stakeholders are encouraged to visit SeaStar Medical's website or connect via LinkedIn and X.

MWN-AI** Analysis

SeaStar Medical Holding Corporation (Nasdaq: ICU) presents an intriguing investment opportunity ahead of its appearance at NobleCon21 on December 3, 2025. The company is centered on addressing acute kidney injury (AKI) through its innovative Selective Cytopheretic Device (SCD) technology and its FDA-approved QUELIMMUNE (SCD-PED) therapy for pediatric patients suffering from sepsis-related complications. This direct alignment with critical healthcare needs, coupled with the sole FDA approval for such a rare condition, positions SeaStar as a potential leader in its niche market.

Investors should keenly observe the upcoming presentation for insights on further developments regarding the pivotal trial of the SCD therapy in adults, which encompasses a significant patient population in the U.S. Given that over 200,000 adults face the challenges of AKI annually and currently lack effective treatment avenues, successful outcomes in this trial could catalyze substantial growth for SeaStar.

As investors, it is crucial to assess not just the technology's potential but also the company's strategic plans for commercialization. SeaStar's Breakthrough Device Designation from the FDA for multiple indications signifies favorable regulatory dynamics, which could translate to more efficient market accessibility and reimbursement pathways.

Market analysts suggest viewing the upcoming NobleCon presentation as a catalyst for reflecting on the company’s growth trajectory within the broader healthcare sector. Increased visibility and investor interest might unlock substantial opportunities, particularly if management outlines solid strategies for scaling operations and addressing investor concerns. Following the conference, the replay, accessible until January 3, 2026, will be essential for tracking any actionable insights that emerge from CEO Eric Schlorff’s dialogue. As SeaStar Medical continues to carve a niche in critical care solutions, it may represent a unique investment opportunity in an undercapitalized sector.

**MWN-AI Summary and Analysis is based on asking OpenAI to summarize and analyze this news release.

Source: GlobeNewswire

DENVER, Nov. 20, 2025 (GLOBE NEWSWIRE) -- SeaStar Medical Holding Corporation (Nasdaq: ICU), a commercial-stage healthcare company focused on transforming treatments for critically ill patients facing organ failure and potential loss of life, announced today that Eric Schlorff, Chief Executive Officer of SeaStar Medical, will present at NobleCon21 - Noble Capital Markets’ Twenty First Annual Emerging Growth Equity Conference at Florida Atlantic University, Executive Education Complex, in Boca Raton, Florida on Wednesday, December 3 rd at 4:00 pm Eastern Standard Time.

Interested investors and guests of SeaStar Medical are welcome to attend the conference. Please register here using the code ICUNOBLECON for the SeaStar Medical participation rate.

A replay of the presentation will be available on Thursday, December 4 th after 4:00 pm Eastern Standard Time on the Company's website and can be accessed here . The replay will be available for up to 30 days following its posting.

About SeaStar Medical

SeaStar Medical is a commercial-stage healthcare company focused on transforming treatments for critically ill patients facing organ failure and potential loss of life. The QUELIMMUNE (SCD-PED) therapy is SeaStar Medical’s first commercial product based on its patented Selective Cytopheretic Device (SCD) technology. The QUELIMMUNE (SCD-PED) therapy was approved in 2024 by the U.S. Food and Drug Administration (FDA). It is the only FDA approved product for the ultra-rare condition of life-threatening acute kidney injury (AKI) due to sepsis or a septic condition in critically ill pediatric patients. SeaStar Medical’s Selective Cytopheretic Device (SCD) therapy has been awarded Breakthrough Device Designation for six therapeutic indications by the FDA, enabling the potential for a speedier pathway to approval and preferable reimbursement dynamics at commercial launch. The company is currently conducting a pivotal trial of its SCD therapy in adult patients with AKI requiring continuous renal replacement therapy (CRRT), a life-threatening condition with no effective treatment options that impacts over 200,000 adults in the U.S. annually.

For more information visit www.seastarmedical.com or visit us on LinkedIn or X .

Contact:
SeaStar Investor Relations:
IR@SeaStarMed.com


FAQ**

What are the key differentiators of SeaStar Medical Holding Corporation ICU's QUELIMMUNE therapy compared to existing treatments for acute kidney injury (AKI)?

SeaStar Medical Holding Corporation's QUELIMMUNE therapy uniquely targets kidney inflammation and immune response to enhance renal recovery in acute kidney injury (AKI) patients, differing from existing treatments that primarily focus on symptomatic relief rather than underlying causes.

How does SeaStar Medical Holding Corporation ICU plan to leverage its Breakthrough Device Designation for future product approvals and market expansions?

SeaStar Medical Holding Corporation ICU aims to leverage its Breakthrough Device Designation to expedite regulatory approvals, enhance market credibility, and facilitate strategic partnerships, ultimately driving broader adoption and revenue growth for its innovative renal therapies.

Can SeaStar Medical Holding Corporation ICU provide updates on the progress and outcomes of the ongoing pivotal trial for adult patients with AKI?

As of my last update in October 2023, SeaStar Medical Holding Corporation has not released specific updates on the progress and outcomes of its ongoing pivotal trial for adult patients with acute kidney injury (AKI), so please check their latest announcements for the most current information.

What strategies is SeaStar Medical Holding Corporation ICU implementing to enhance investor confidence and attract more investments during emerging growth events like NobleCon21?

SeaStar Medical Holding Corporation ICU is enhancing investor confidence and attracting more investments during emerging growth events like NobleCon21 by showcasing its innovative medical technologies, strong leadership, and robust market potential through strategic presentations and stakeholder engagement.

**MWN-AI FAQ is based on asking OpenAI questions about SeaStar Medical Holding Corporation (NASDAQ: ICU).

SeaStar Medical Holding Corporation

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