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OKYO Pharma to Present at the Bio International Convention

MWN-AI** Summary

OKYO Pharma Limited, a clinical-stage biopharmaceutical company focused on innovative treatments for ocular conditions, will have its CEO, Dr. Gary S. Jacob, present at the Bio International Convention in Boston, MA from June 16-19, 2025. His presentation, titled "Clinical Development of Urcosimod to Treat Neuropathic Corneal Pain," will highlight the promising developments of OKYO’s lead drug candidate, urcosimod, aimed at addressing neuropathic corneal pain (NCP). This condition, which results in severe ocular discomfort, currently lacks an FDA-approved treatment.

NCP is characterized by debilitating pain and sensitivity in the eyes and face, often arising from nerve damage combined with inflammation. Available treatments are limited and generally applied off-label, underscoring the significance of drug candidates like urcosimod. Urcosimod, previously known as OK-101, is a lipid-conjugated chemerin peptide agonist that targets the ChemR23 receptor present on immune and neural cells in the eye. Its innovative design—featuring a lipid anchor—enhances its retention in the ocular environment, potentially increasing its efficacy in reducing pain and inflammation.

The drug has already demonstrated promising results in preclinical studies and Phase 2 trials for dry eye disease, showing statistically significant outcomes in multiple endpoints. OKYO Pharma is currently advancing urcosimod through a recently completed Phase 2 trial specifically for NCP patients, further asserting its commitment to addressing this significant medical need in ocular health.

Investors and stakeholders interested in the latest developments in biopharmaceuticals are encouraged to follow OKYO as it strives to deliver groundbreaking therapies in the ophthalmic field. More information can be found at www.okyopharma.com.

MWN-AI** Analysis

As OKYO Pharma Limited (NASDAQ: OKYO) prepares for its presentation at the Bio International Convention, investors should consider several factors influencing the company's stock and its prospects. The focus of the presentation will be on urcosimod, OKYO’s lead drug candidate, which represents a significant opportunity in a market currently lacking FDA-approved therapies for neuropathic corneal pain (NCP).

The presentation by Dr. Gary S. Jacob will detail the promising early-stage clinical data of urcosimod, which has shown anti-inflammatory and analgesic effects in treating ocular conditions. The recent success of urcosimod in a Phase 2 trial for dry eye disease, combined with its ongoing evaluations for NCP, positions OKYO favorably within a niche yet critical market for ocular pain management. Given that NCP affects thousands of patients globally, the potential demand for an effective treatment is substantial.

As OKYO continues to advance its clinical trials, particularly the just-completed study involving NCP patients, investors should monitor updates on trial results and their subsequent impact on the company’s valuation. Previous trials have demonstrated statistical significance, which not only builds confidence in urcosimod’s efficacy but also enhances the company’s credibility within the biopharmaceutical sector.

Moreover, upcoming data releases, including any future trial findings, could drive stock volatility and present trading opportunities. Investors may want to take a strategic approach, considering buying on dips, especially in the lead-up to trial announcements.

In summary, OKYO Pharma offers a compelling investment opportunity driven by innovative therapeutic development and strategic clinical advancements. Keeping abreast of the upcoming presentation and subsequent clinical trial results will be key for investors looking to capitalize on potential growth in OKYO’s stock price.

**MWN-AI Summary and Analysis is based on asking OpenAI to summarize and analyze this news release.

Source: GlobeNewswire

LONDON and NEW YORK, June 11, 2025 (GLOBE NEWSWIRE) -- OKYO Pharma Limited (NASDAQ: OKYO ), a clinical-stage biopharmaceutical company developing innovative therapies for the treatment of neuropathic corneal pain, a severe ocular condition without an FDA approved therapy, and for inflammatory eye diseases, announced that its CEO, Gary S. Jacob, Ph.D., will be giving an oral presentation during the Bio International Convention in Boston, MA. Dr. Jacob’s presentation will cover the development of urcosimod, OKYO’s lead clinical drug candidate, to treat neuropathic corneal pain (NCP) which is a debilitating condition affecting many tens of thousands worldwide, and is characterized by chronic, severe eye discomfort.

Presentation Information:

Event: Bio International Convention 2025

Presenter: Dr. Gary S. Jacob, CEO of OKYO Pharma

Presentation Title: Clinical Development of Urcosimod to Treat Neuropathic Corneal Pain

Convention Dates: June 16–19, 2025

Location: Boston Convention & Exhibition Center, Boston, MA

About Neuropathic Corneal Pain (NCP)
NCP is a condition that causes severe pain and sensitivity of the eyes, face, or head. The exact cause of NCP is unknown but is thought to result from nerve damage to the cornea combined with inflammation . NCP, which can exhibit as a severe, chronic, debilitating condition in patients suffering from a host of ophthalmic conditions, is presently treated, with limited success, by various topical and systemic treatments in an off-label fashion.

About Urcosimod (formerly called OK-101)
Urcosimod is a lipid conjugated chemerin peptide agonist of the ChemR23 G-protein coupled receptor which is typically found on immune cells of the eye responsible for the inflammatory response, as well as on neurons and glial cells in the dorsal root ganglion. Urcosimod was developed using a membrane-anchored-peptide technology to produce a novel long-acting drug candidate for treating dry eye disease. Urcosimod has been shown to produce anti-inflammatory and pain-reducing activities in mouse models of dry eye disease and corneal neuropathic pain, respectively, and is designed to combat washout through the inclusion of the lipid anchor built into the drug molecule to potentially enhance the residence time of urcosimod within the ocular environment. Urcosimod showed clear statistical significance in multiple endpoints in a 240-patient Phase 2, multi-center, double-masked, placebo-controlled trial to treat dry eye disease, and is presently being evaluated in a just-completed randomized, placebo-controlled, double-masked Phase 2 trial involving 17 neuropathic corneal pain patients.

About OKYO
OKYO Pharma Limited (NASDAQ: OKYO) is a clinical stage biopharmaceutical company developing innovative therapies for the treatment of neuropathic corneal pain and dry eye disease, with ordinary shares listed for trading on the NASDAQ Capital Market. OKYO is focused on the discovery and development of novel molecules to treat neuropathic corneal pain and ocular diseases. In addition to the completed Phase 2 trial of urcosimod to treat dry eye disease patients, OKYO is also currently evaluating urcosimod to treat neuropathic corneal pain patients in a Phase 2 trial.

For further information, please visit www.okyopharma.com .

Enquiries:

OKYO Pharma Limited Gary S. Jacob, Chief Executive Officer 917-497-7560
Business Development & Investor Relations Paul Spencer +44 (0)20 7495 2379

FAQ**

How does the upcoming presentation by Dr. Gary S. Jacob of OKYO Pharma Limited OKYO at the Bio International Convention in Boston impact investor perceptions regarding the future of neuropathic corneal pain treatments?

Dr. Gary S. Jacob's presentation at the Bio International Convention may bolster investor confidence in OKYO Pharma Limited's innovative approach to neuropathic corneal pain treatments, highlighting potential advancements and market opportunities in this therapeutic area.

What are the implications for OKYO Pharma Limited OKYO's stock performance following the completion of the Phase 2 trial results for urcosimod, particularly in the competitive biopharmaceutical landscape?

The completion of Phase 2 trial results for urcosimod could significantly impact OKYO Pharma Limited's stock performance by establishing its market potential, influencing investor sentiment, and positioning it against competitors in the biopharmaceutical landscape.

How might potential FDA approval for urcosimod by OKYO Pharma Limited OKYO influence market dynamics within the ocular pain treatment sector, especially in relation to existing therapies?

Potential FDA approval for urcosimod by OKYO Pharma Limited could disrupt the ocular pain treatment sector by introducing a new, potentially more effective therapy, leading to increased competition for existing treatments and possibly shifting market share among providers.

In what ways could the launch of urcosimod for neuropathic corneal pain change the strategic direction of OKYO Pharma Limited OKYO, particularly in its research and development efforts?

The launch of urcosimod for neuropathic corneal pain could pivot OKYO Pharma Limited’s strategic direction by enhancing its focus on ophthalmic therapeutics, attracting partnerships and funding, and potentially expanding its R&D towards innovative pain management solutions.

**MWN-AI FAQ is based on asking OpenAI questions about OKYO Pharma Limited (NASDAQ: OKYO).

OKYO Pharma Limited

NASDAQ: OKYO

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