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Tyra Biosciences Announces Poster Presentations at the 2026 ASCO® Genitourinary (GU) Cancers Symposium

MWN-AI** Summary

Tyra Biosciences, Inc. (Nasdaq: TYRA), a clinical-stage biotechnology firm specializing in precision medicines for Fibroblast Growth Factor Receptor (FGFR) biology, has announced important findings that will be presented at the 2026 ASCO® Genitourinary (GU) Cancers Symposium. This event, taking place from February 26-28, 2026, in San Francisco, will feature two key abstracts highlighting Tyra's innovative therapies.

The first presentation titled "ctDNA monitoring of FGFR3-altered metastatic urothelial cancer treated with dabogratinib (formerly TYRA-300) in the SURF301 trial" (Abstract Number: 809) will occur during the Poster Session B on February 27, from 11:30 AM to 12:45 PM PST. Andrew J. Murtha from the University of British Columbia will present research that focuses on circulating tumor DNA (ctDNA) monitoring, which is pivotal for understanding responses to treatment in patients with FGFR3-altered metastatic urothelial cancer.

The second abstract, "A phase 2 multicenter, open-label study evaluating the efficacy and safety of dabogratinib in participants with FGFR3-altered low-grade, intermediate risk non-muscle invasive bladder cancer (SURF302)" (Abstract Number: TPS886), will also be presented on February 27 in the Trials in Progress Poster Session B. Dr. Gautam Jayram from Urology Associates will lead this presentation, sharing insights into the potential benefits of dabogratinib as a targeted therapy.

Tyra’s investigational drug pipeline includes dabogratinib, recognized as a first-in-class FGFR3 inhibitor, and other promising candidates aimed at various FGFR-related cancers. For updates and further details, interested parties can visit Tyra Biosciences' website or check the ASCO GU event platform.

MWN-AI** Analysis

Tyra Biosciences, Inc. (Nasdaq: TYRA) has recently made headlines with its announcement of two accepted abstract presentations at the 2026 ASCO® Genitourinary (GU) Cancers Symposium. The presentations will shed light on the efficacy of the oral FGFR3 inhibitor, dabogratinib, emphasizing Tyra’s commitment to developing targeted therapies for urothelial carcinoma and non-muscle invasive bladder cancer.

From an investment perspective, the company's engagement at such a prestigious symposium indicates a robust pipeline and the potential for clinical breakthroughs that could significantly enhance their market position. The scientific discussions surrounding ctDNA monitoring and the efficacy of dabogratinib not only demonstrate Tyra's innovation in FGFR biology but also highlight the increasing validation of their precision medicine platform, SNÅP.

Investors should be aware that clinical-stage biotechs often experience volatility, impacted by clinical data releases and market perceptions of their research outcomes. Thus, it's crucial for stakeholders to closely monitor commentary emerging from the ASCO GU presentations for insights into dabogratinib’s performance and its reception by the medical community. Positive feedback could catalyze upward momentum in TYRA's stock price, while any adverse results or skepticism could yield downward pressure.

Analysts should also evaluate Tyra's competitive landscape, particularly against other biotech firms focusing on FGFR inhibitors. Considering Tyra’s commitment to advancing their clinical trials—including those for pediatric applications—there lies substantial long-term growth potential.

In summary, while the inherent risks of clinical-stage investments persist, Tyra Biosciences showcases promising avenues for strategic growth in precision oncology. Current investors might consider a hold strategy, while potential buyers should wait for further data validation post-ASCO GU. Overall, attentive monitoring of upcoming results and broader healthcare trends will be essential for making informed decisions in this dynamic sector.

**MWN-AI Summary and Analysis is based on asking OpenAI to summarize and analyze this news release.

Source: PR Newswire

PR Newswire

CARLSBAD, Calif., Feb. 23, 2026 /PRNewswire/ -- Tyra Biosciences, Inc. (Nasdaq: TYRA), a clinical-stage biotechnology company focused on developing next-generation precision medicines that target large opportunities in Fibroblast Growth Factor Receptor (FGFR) biology, announced today that two abstracts have been accepted for presentation at the 2026 ASCO® Genitourinary (GU) Cancers Symposium (ASCO GU). The meeting is being held February 26-28, 2026, in San Francisco, California.

Details of the poster presentations are below:

Title: "ctDNA monitoring of FGFR3-altered metastatic urothelial cancer treated with dabogratinib (formerly TYRA-300) in the SURF301 trial"

  • Abstract Number: 809
  • Session: Poster Session B: Prostate Cancer and Urothelial Carcinoma
  • Date and Time: February 27, 2026, 11:30 AM–12:45 PM PST
  • Presenting Author: Andrew J. Murtha, BSc, University of British Columbia, Vancouver, BC, Canada

Title: "A phase 2 multicenter, open-label study evaluating the efficacy and safety of dabogratinib (formerly TYRA-300) in participants with FGFR3-altered low-grade, intermediate risk non-muscle invasive bladder cancer (SURF302)"

  • Abstract Number: TPS886
  • Session: Trials in Progress Poster Session B: Urothelial Carcinoma
  • Date and Time: February 27, 2026, 11:30 AM–12:45 PM PST
  • Presenting Author: Gautam Jayram, MD, Urology Associates, Nashville, TN

More information can be found at the ASCO GU website. The posters will be available on the IR page of TYRA's website following presentation at ASCO GU: https://ir.tyra.bio.

About Tyra Biosciences

Tyra Biosciences, Inc. (Nasdaq: TYRA) is a clinical-stage biotechnology company focused on developing next-generation precision medicines that target large opportunities in FGFR biology. TYRA's in-house precision medicine platform, SNÅP, enables rapid and precise drug design through iterative molecular SNÅPshots that help predict genetic alterations most likely to cause acquired resistance to existing therapies. TYRA's expertise in FGFR biology has created a differentiated pipeline with clinical-stage programs in targeted oncology and genetically defined conditions. TYRA's lead precision medicine stemming from SNÅP, oral dabogratinib, is a potential first-in-class selective FGFR3 inhibitor. Oral dabogratinib's current planned clinical development includes three Phase 2 studies: SURF303 for low-grade upper tract urothelial carcinoma, SURF302 for intermediate risk non-muscle invasive bladder cancer, and BEACH301 for pediatric achondroplasia. TYRA is also developing TYRA-430, an oral, investigational FGFR4/3-biased inhibitor for FGF19+/FGFR4-driven cancers, in the SURF431 study for advanced hepatocellular carcinoma, and TYRA-200, an oral, investigational, FGFR1/2/3 inhibitor, in the SURF201 study for metastatic intrahepatic cholangiocarcinoma. TYRA is based in Carlsbad, CA.

For more information about our science, pipeline and people, please visit www.tyra.bio and engage with us on LinkedIn.

Contact:
Amy Conrad
aconrad@tyra.bio

 

SOURCE Tyra Biosciences

FAQ**

What key findings can be expected from the poster presentation titled "ctDNA monitoring of FGFR3-altered metastatic urothelial cancer treated with dabogratinib" by Tyra Biosciences Inc. TYRA at the ASCO GU Symposium?

The poster presentation by Tyra Biosciences Inc. will likely reveal insights on the efficacy of ctDNA as a biomarker for monitoring treatment response in patients with FGFR3-altered metastatic urothelial cancer receiving dabogratinib.

How does Tyra Biosciences Inc. TYRA plan to leverage the results from its SURF302 study on dabogratinib for FGFR3-altered non-muscle invasive bladder cancer in future clinical trials?

Tyra Biosciences Inc. plans to leverage the SURF302 study results on dabogratinib for FGFR3-altered non-muscle invasive bladder cancer to support the design and optimization of future clinical trials, enhancing treatment efficacy and patient selection strategies.

What implications do the poster presentations by Tyra Biosciences Inc. TYRA have for the company's overall pipeline and strategy in FGFR-targeted cancer treatments?

The poster presentations by Tyra Biosciences Inc. suggest a strong commitment to advancing their FGFR-targeted cancer treatments, potentially enhancing their pipeline’s credibility, attracting investment, and reinforcing their competitive position in oncology therapeutics.

How could the data presented at the ASCO GU Symposium support Tyra Biosciences Inc. TYRA’s position in the competitive landscape of precision oncology?

The data presented at the ASCO GU Symposium could bolster Tyra Biosciences Inc.'s position in precision oncology by demonstrating the efficacy and safety of its targeted therapies, thereby highlighting its innovative approach and potential to address unmet needs in the market.

**MWN-AI FAQ is based on asking OpenAI questions about Tyra Biosciences Inc. (NASDAQ: TYRA).

Tyra Biosciences Inc.

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