PYXS - Pyxis Oncology Announces Four Abstracts Accepted for Poster Presentation at Society for Immunotherapy of Cancer (SITC) 2023 | Benzinga
BOSTON, Sept. 27, 2023 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (NASDAQ:PYXS), a clinical-stage company focused on developing next-generation therapeutics to target difficult-to-treat cancers, today announced four abstracts for four different assets have been accepted for poster presentation at the Society for Immunotherapy of Cancer (SITC) 38th Annual Meeting to be held November 1-5, 2023, in San Diego.
"We look forward to presenting a trial-in-progress poster for PYX-201, our first-in-class and first-in-concept tumor stroma-targeting antibody-drug conjugate (ADC), and we are gratified by the investigator interest and enthusiasm for our Phase 1 trial," said Lara S. Sullivan, M.D., President and Chief Executive Officer of Pyxis Oncology. "Pyxis Oncology is proud to be a pioneer in stromal therapeutics, and in our view, targeting the tumor stroma represents a promising new approach to cancer therapy that is designed to damage the barrier that protects, feeds and provides structure to the tumor. PYX-201 employs a linker-payload combination that demonstrated an acceptable safety profile and dose-dependent anti-tumor activity in prior clinical trials. We continue to expect to see preliminary data from this study, including biomarker results and early signs of potential clinical activity, in early 2024."
Dr. Sullivan continued, "Additionally, we are proud of the progress our team has made in advancing PYX-106, a fully human immunotherapy antibody candidate in development that blocks the activity of Siglec-15, for which we will also be presenting a trial-in-progress poster, reflecting our operational progress. We are pleased to share the insights we have generated through our pre-clinical work on PYX-102, our KLRG-1 antibody, which was deprioritized in 2022 and is available for licensing/collaboration, as well as sotigalimab or PYX-107, our newly acquired CD40 agonist from Apexigen, acquired through the close our acquisition as announced on August 23, 2023. We ...