PFE - This Twice Daily Weight Loss Drug Has Adverse Side Effects And Pfizer Wants To Discontinue It | Benzinga
Pfizer Inc (NYSE: PFE) reported topline data from the Phase 2b trial investigating its oral weight loss drug Glucagon-like peptide-1 receptor agonist (GLP-1RA) candidate, danuglipron (PF-06882961), in adults with obesity and without type 2 diabetes.
The company says the study met its primary endpoint, demonstrating a statistically significant change in body weight from baseline, but danuglipron was tied to "high rates” of mild gastrointestinal side effects, leading to more than half of the patients across all dose groups dropping out from the trial.
Twice-daily dosing of the drug showed statistically significant ...