WVE - Wave Life Sciences Announces Upcoming Presentations Highlighting Novel siRNA Program in Obesity and Leadership in RNA Editing | Benzinga
Presentation at the Obesity & Weight Loss Drug Development Summit to review Real World Evidence for the GLP-1 class and the opportunity for Wave's INHBE program as a best-in-class approach for obesity designed to induce fat burning and preserve muscle mass with once or twice-annual subcutaneous administration
Presentations at the RNA Editing Summit to review how Wave is advancing a high-value pipeline of wholly owned RNA editing therapeutics for mRNA correction and upregulation, led by WVE-006 with proof-of-mechanism data on track for 2024
CAMBRIDGE, Mass., June 12, 2024 (GLOBE NEWSWIRE) -- Wave Life Sciences Ltd. (NASDAQ:WVE), a clinical-stage biotechnology company focused on unlocking the broad potential of RNA medicines to transform human health, today announced upcoming presentations at the 2nd Annual Obesity & Weight Loss Drug Development Summit and the 5th Annual RNA Editing Summit, both taking place in Boston on June 11-13 and June 18-20, respectively.
"Our presentations at these upcoming conferences highlight the potential of our growing, wholly owned pipeline, where we are combining novel genetic insights with our best-in-class siRNA and RNA editing capabilities to develop new treatment approaches for rare and common diseases with high unmet needs," said Erik Ingelsson, MD, PhD, Chief Scientific Officer at Wave Life Sciences. "Our INHBE silencing program reimagines obesity treatment, focusing not just on weight loss, but on the restoration and maintenance of a healthy metabolic profile. As we will highlight at the Obesity Summit, this profile may also overcome challenges with the GLP-1 class, including unwanted side effects, poor adherence, and rebound weight gain. With RNA editing, we continue to lead the field with our WVE-006 program in Alpha-1 antitrypsin deficiency, where we have initiated our RestorAATion-2 study for individuals with AATD and expect to deliver proof-of-mechanism data this year, which would be the first-ever for RNA editing. In addition to WVE-006, we are advancing a pipeline of RNA editing therapeutics across a range of high-impact hepatic and extra-hepatic targets, and this work is being accelerated using our proprietary ‘Edit-verse' that maps the editable gene-disease network. We are looking forward to presenting this pioneering work at the summits."
Presentation Details:
2nd Annual Obesity & Weight Loss Drug Development Summit
- Analyzing Real-World Evidence Regarding Efficacy, Adherence and Usage of GLP-1 Drugs and New Therapeutic Directions (Ginnie Yang, PhD, Senior Vice President, Translational Medicine, Wave Life Sciences)
Thursday, June 13, 2024 from 11:15-11:45 am ET
5th Annual RNA Editing Summit
- Unlocking the Edit-Verse: Combining Machine Learning & Multiple AIMer Applications to Build a High-Impact RNA Editing Pipeline (Ginnie ...