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There's news today that bluebird bio has suspended its gene therapy work on sickle cell disease because of two cases of cancer in its treatment population.
Survival rates for bone marrow transplants in general have steadily improved over the years, and everyone knows that one of the rough parts is the pre-treatment.
But that problem might or might not get solved in time to help out bluebird (or to quell the worries that other gene-therapy outfits might have who are also targeting that hematopoietic tissue).