GLMD - Intercept Gilead Pfizer And Genfit In NASH: Overview Of Q1 2019 Catalysts In Liver Therapeutics Investments
Clinical Trials
NASH is a progressive chronic liver disease with many causal pathogenic factors. We have learnt from research that dysregulation of the glucose and lipid metabolic pathways could be associated with the development of NASH. Inflammation and activation of the apoptotic (i.e. cell death) machinery have both been reported to promote the development of NASH. NASH is often labeled a ‘silent disease’ because it is asymptomatic. Internally, the effects of NASH in the body is not a silent effect, with its pathogenic effects in the liver now being increasingly recognized: steatosis (i.e. fatty liver),