PFE - Oxford T-Spot test shows key role of T cells in COVID-19 immunity
Oxford Immunotec Global PLC ([[OXFD]] +0.8%) announces results from a prospective study in the U.K. that demonstrated the ability of its T-SPOT Discovery SARS-CoV-2 test to detect PCR-confirmed COVID-19 infections that were negative via blood (serology) tests for antibodies.T-SPOT, for research use only, detects the levels of T cells, immune cells that attack infected cells instead of the virus directly like antibodies. T cell responses are a key component of immunity and may be sufficient to provide longer term protection from COVID-19 since antibody levels appear to drop fairly quickly after infection.In this study, T cell tests were conducted on almost 3K participants at enrollment, then followed for subsequent COVID-19 infection confirmed by molecular test ((PCR)). None of the subjects with high T cell response developed symptomatic SARS-CoV-2 infection in the follow-up period while there were 20 confirmed infections in the low T cell response group.The data suggest that blood
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Oxford T-Spot test shows key role of T cells in COVID-19 immunity