SPPI - Spectrum stock rises 7% on positive data of poziotinib in lung cancer study

Spectrum Pharmaceuticals (NASDAQ:SPPI) said the group 4 of a trial called ZENITH20 met its main goal evaluating poziotinib in certain patients with non-small lung cancer (NSCLC) who had not received prior therapy. The ZENITH20 study consists of seven cohorts. This data was from 70 first-line patients with NSCLC with HER2 exon 20 insertion mutations. The company said the results showed a confirmed objective response rate (ORR) (percentage of patients whose disease decreased) of 41% including one complete response. The evaluable patient population showed an ORR of 50%. The company added that the study met its primary goal as the observed lower bound of 30% exceeded the pre-specified lower bound of 20%. The secondary goals included, disease control rate (DCR) which was was 73%; duration of response (DoR) was 5.7 months; and progression-free survival (PFS) (the length of time a patient lives with the disease without getting worse) was 5.6 months. The most common treatment related

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Spectrum stock rises 7% on positive data of poziotinib in lung cancer study