- Median overall survival of 13.4 months in patients treated with the Bria-IMT™ combination regimen (vs. 6.7-9.8 months for similar patients reported in the literature*).
- 32 out of 42 patients treated since 2022 remain alive suggesting consistently strong survival benefit.
- All patients were able to receive therapy with no toxicity related discontinuations.
PHILADELPHIA and VANCOUVER, British Columbia, Dec. 06, 2023 (GLOBE NEWSWIRE) -- BriaCell Therapeutics Corp. (NASDAQ:BCTX, BCTXW)) (TSX:BCT) ("BriaCell" or the "Company"), a clinical-stage biotechnology company that develops novel immunotherapies to transform cancer care, is thrilled to announce continued outstanding topline survival and clinical benefit data in advanced metastatic breast cancer patients treated Bria-IMT™ in combination with an immune check point inhibitor (CPI). The data is being revealed at the 2023 San Antonio Breast Cancer Symposium® held at Henry B. Gonzalez Convention Center, San Antonio, TX.
"The survival data in this heavily pre-treated advanced metastatic breast cancer patients looks very promising and we are looking forward to validate these findings in the PREVAIL trial "Importantly, the favorable safety profile makes the novel treatment regimen an attractive choice for patients who are heavily pre-treated and often cannot tolerate the harsh side effects of other therapies." stated Carmen Calfa, M.D., Clinical Research Lead for the breast site disease group at the University of Miami Miller School of Medicine, Co-Director of the Cancer Survivorship Program at Sylvester Comprehensive Cancer Center, and Principal Clinical Investigator of the Phase 2 Bria-IMT™ study.
Abstract Title: Randomized Phase 2 of Bria-IMT™, an Allogenic Human Cell Line with Antigen Presenting Activity, in Heavily Pretreated Metastatic Breast Cancer
Submission ID: 1580375
Presentation ID: PO3-05-12
Spotlight Session: Poster Session 3
Session Date and Time: Thursday December 7, 2023 12:00 PM - 2:00 PM CT
Phase 2 Combination Study of Bria-IMT™ with Immune Check ...