A revolutionary cell-based gene therapy is showing promise for treating autoimmune diseases.
Professor Georg Schett, a rheumatologist at University Hospital Erlangen in eastern Germany, used chimeric antigen receptor (CAR-T) cell therapy, typically used for blood cancers, for autoimmune conditions like lupus, when the immune system attacks healthy cells and tissues by mistake. This attack causes inflammation.
The Financial Times writes that the early success of CAT-T therapy has reignited discussions about its potential beyond blood cancers, though challenges remain.
Professor Georg Schett noted that this approach could revolutionize autoimmune disease treatment, providing a one-time intervention instead of the ongoing immune suppression traditionally required.
Despite only one of 15 patients experiencing a mild disease recurrence, the enthusiasm ...