- Aricept and blarcamesine limit further oxidative stress in Alzheimer's disease via agonism of Sigma-1 receptors. Simufilam may do the same.
- Aricept, blarcamesine, and simufilam either directly or indirectly increase ketone levels which catalyze the decomposition of the nitro-oxidant peroxynitrite.
- Blarcamesine may also be a peroxynitrite scavenger.
- East Asian herbs which also are peroxynitrite scavengers produce better results in terms of cognition than conventional Alzheimer's medications by themselves.
- Blarcamesine is one of the very best drug candidates for the treatment of Alzheimer's disease.
For further details see:
Anavex's Blarcamesine And Cassava Sciences' Simufilam: The Stabilization Period For Alzheimer's Disease