- Cassava Sciences may have removed an outlier in the drug group turning a negative result into a positive one, leading to a windfall for its CEO and chief scientific investigator.
- Cassava Sciences stated mechanisms of action do not explain its results.
- Simufilam may be a sigma-1 receptor agonist like Aricept and Anavex 2-73 and may be a peroxynitrite decomposition catalyst which may explain its benefits in regards to cognition.
- Peroxynitrite scavengers such as Anavex 2-73 appear to produce better results over longer periods of time.
For further details see:
Cassava Sciences And Alzheimer's Disease: Unravelling Some Of The Puzzle