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Connect Biopharma Announces Two Oral Presentations at the European Academy of Allergy and Clinical Immunology (EAACI) 2025 Annual Congress

MWN-AI** Summary

Connect Biopharma Holdings Limited (Nasdaq: CNTB), a clinical-stage biopharmaceutical firm specializing in innovative treatments for asthma and chronic obstructive pulmonary disease (COPD), announced its participation in the upcoming European Academy of Allergy and Clinical Immunology (EAACI) 2025 Annual Congress, held from June 13 to 16 in Glasgow, UK. The company is set to present two oral presentations showcasing the efficacy of its lead candidate, Rademikibart, an anti-interleukin-4-receptor alpha (IL-4R?) antibody.

The presentations will be delivered by Dr. Rekha Chaudhuri during the "Clinical Trials on Airways Diseases" session on June 13 from 3:00 PM to 4:30 PM BST. The first presentation, titled "Reduction in Annualized Exacerbations with Rademikibart in Eosinophilic Driven, Type 2 Asthma," will delve into the drug's impact on decreasing the frequency of severe asthma episodes. The second presentation, "Improvement in Lung Function with Rademikibart in Eosinophilic Driven, Type 2 Asthma," will highlight how the treatment enhances lung function among asthma patients.

Rademikibart is positioned to address significant unmet needs in asthma and COPD care, particularly for the approximately 1 million asthma patients and 1.3 million COPD patients in the U.S. experiencing acute exacerbations each year. In its Phase 2 trial, Rademikibart demonstrated promising efficacy, with notable reductions in exacerbations and rapid improvement in forced expiratory volume (FEV1). Results indicated statistically significant enhancements detectable as early as 24 hours post-administration.

Following the congress, the presentations will be made available on Connect Biopharma’s website, underscoring the company’s commitment to advancing respiratory health innovations. More detailed information can be found at www.connectbiopharm.com.

MWN-AI** Analysis

Connect Biopharma Holdings Limited (Nasdaq: CNTB) has made significant strides in addressing acute and chronic care of asthma and chronic obstructive pulmonary disease (COPD), particularly with their product rademikibart, a novel anti-IL-4R? antibody. The company’s participation in the European Academy of Allergy and Clinical Immunology (EAACI) 2025 Annual Congress, where they will present the efficacy of rademikibart in improving asthma outcomes, is a pivotal moment that could influence investor sentiment and stock performance.

Investors should closely monitor the presentations scheduled for June 13, 2025, focusing on two critical abstracts that explore rademikibart's impact on reducing annualized exacerbations and improving lung function in eosinophilic-driven, type 2 asthma. Given the promising Phase 2 trial results showcasing significant reductions in exacerbations and rapid improvements in Forced Expiratory Volume (FEV1), successful data disclosures at EAACI may lead to increased market confidence and potential price appreciation for CNTB shares.

Furthermore, there’s a substantial unmet need in the asthma and COPD treatment markets, highlighted by the statistics that over 2.3 million patients in the U.S. experience acute exacerbations annually. If rademikibart continues to demonstrate its efficacy, it could position Connect Biopharma as a significant player in this market, creating further opportunity for revenue growth and investment returns.

However, investors should also be aware of the inherent risks involving clinical-stage biopharmaceutical companies, including regulatory hurdles and the unpredictability of clinical trial outcomes. Therefore, while monitoring upcoming presentations, maintaining a balanced investment approach—considering both the opportunities and risks—will be crucial for prudent portfolio management.

In conclusion, the upcoming presentations at EAACI could present a catalytic moment for Connect Biopharma. Stakeholders would do well to remain engaged and assess the data's impact on the stock trajectory post-event.

**MWN-AI Summary and Analysis is based on asking OpenAI to summarize and analyze this news release.

Source: GlobeNewswire

SAN DIEGO, June 03, 2025 (GLOBE NEWSWIRE) -- Connect Biopharma Holdings Limited (Nasdaq: CNTB) (“Connect Biopharma” or the “Company”), a clinical-stage biopharmaceutical company focused on transforming acute and chronic care of asthma and chronic obstructive pulmonary disease (COPD), today announced two oral presentations at the European Academy of Allergy and Clinical Immunology (EAACI) 2025 Annual Congress, taking place June 13-16, 2025, in Glasgow, United Kingdom and virtually.

The presentation details are as follows:

Abstract Title: Reduction in Annualized Exacerbations with Rademikibart in Eosinophilic Driven, Type 2 Asthma
Abstract Number: 001671
Presenter: Rekha Chaudhuri, M.D.
Session Title: Clinical Trials on Airways Diseases
Date and Time: Friday, June 13 th from 3:00 p.m. – 4:30 p.m. BST

Abstract Title: Improvement in Lung Function with Rademikibart in Eosinophilic Driven, Type 2 Asthma
Abstract Number: 001678
Presenter: Rekha Chaudhuri, M.D.
Session Title: Clinical Trials on Airways Diseases
Date and Time: Friday, June 13 th from 3:00 p.m. – 4:30 p.m. BST

Following the presentations, each presentation will be available on Connect’s website under the presentations and publications section .

About Connect Biopharma and Rademikibart
Connect Biopharma is a clinical-stage biopharmaceutical company dedicated to transforming care for asthma and COPD. Headquartered in San Diego, California, the company is advancing rademikibart, a next-generation, potentially best-in-class anti-interleukin-4-receptor alpha (IL-4R?) antibody. With an initial focus on acute exacerbations—an area with significant unmet need—rademikibart has the potential to also drive chronic utilization in asthma and COPD amongst the approximately 1 million asthma patients and 1.3 million COPD patients in the U.S. who experience acute exacerbations annually. In a Phase 2 trial for asthma, rademikibart demonstrated strong efficacy and safety data, with clinically meaningful reductions in exacerbations and rapid, statistically significant improvements in forced expiratory volume in one second (FEV 1 ), observed within one week—and in most cases, within 24 hours via home spirometry.

For more information visit www.connectbiopharm.com .

Investor Relations Contact:

Alex Lobo
Precision AQ
Alex.lobo@precisionaq.com
(212) 698-8802

Media Contact:

Ignacio Guerrero-Ros, Ph.D., or David Schull
Russo Partners, LLC
Ignacio.guerrero-ros@russopartnersllc.com
David.schull@russopartnersllc.com
(858) 717-2310 or (646) 942-5604


FAQ**

What are the anticipated market impacts for Connect Biopharma Holdings Limited (CNTB) following the presentation of Rademikibart's efficacy data at the EAACI 2025 Annual Congress?

The anticipated market impacts for Connect Biopharma Holdings Limited (CNTB) following Rademikibart's efficacy data presentation at the EAACI 2025 Annual Congress could lead to increased investor confidence, potential stock price appreciation, and heightened interest from pharmaceutical partners.

How does Connect Biopharma Holdings Limited (CNTB) plan to leverage the Phase 2 trial results of Rademikibart to attract potential investors and partnerships?

Connect Biopharma Holdings Limited (CNTB) aims to leverage the promising Phase 2 trial results of Rademikibart by showcasing its potential for significant market impact and improved patient outcomes to attract potential investors and partnerships.

Can you provide insights into the regulatory pathway for Connect Biopharma Holdings Limited (CNTB) regarding Rademikibart based on its promising results in asthma and COPD?

Connect Biopharma Holdings Limited (CNTB) will likely follow a sequential regulatory pathway starting with IND submissions, followed by Phase trials, and ultimately seeking FDA approval based on Rademikibart’s efficacy and safety data for asthma and COPD treatments.

What competitive advantages does Connect Biopharma Holdings Limited (CNTB) believe Rademikibart has over existing treatments for eosinophilic-driven asthma and COPD?

Connect Biopharma Holdings Limited believes Rademikibart offers competitive advantages over existing treatments for eosinophilic-driven asthma and COPD through its targeted mechanism of action, potential for improved efficacy, and favorable safety profile.

**MWN-AI FAQ is based on asking OpenAI questions about Connect Biopharma Holdings Limited (NASDAQ: CNTB).

Connect Biopharma Holdings Limited

NASDAQ: CNTB

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