PolarityTE (PTE), a micro-cap biotech in the regenerative medicine space, is truly a hidden gem. The company's lead product is an autologous, homologous SkinTE construct. SkinTE technology is used to regenerate functionally-polarized, hierarchically-organized, hair-bearing skin in full-thickness burns and wounds.
This is dramatically different from the current standard of care for treating burns and wounds, called STSG (split-thickness skin grafts). STSGs involve transplanting 2 layers of the skin, epidermis and very top layer of the dermis, from the unharmed part of the patients' body to the wound site. However, this presents multiple challenges