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CareDx Announces VANTx(TM), an AI?Powered Clinical Data & Analytics Platform Built on CareDx's Proprietary, Large-Scale, Longitudinal Solid Organ Transplant Datasets

MWN-AI** Summary

CareDx, Inc. (Nasdaq: CDNA), a leading precision medicine company focused on organ transplant solutions, has announced the launch of VANTx™, a groundbreaking AI-powered clinical data and analytics platform. This innovative, cloud-native platform debuted at the 2026 Precision Medicine World Conference, aiming to enhance transplant outcomes through advanced cohort analysis and real-world evidence generation.

VANTx is designed to transform complex healthcare data into actionable insights, supporting clinicians, transplant programs, and pharmaceutical partners in the evaluation of treatment trends and patient outcomes. By harnessing CareDx's extensive, longitudinal datasets on solid organ transplant patients, VANTx allows for secure and scalable cohort analyses that can inform treatment protocol developments, clinical research studies, and trial designs.

Jing Huang, CareDx's Chief Data and AI Officer, highlighted the vision behind VANTx during its introduction at the conference. The platform utilizes a sophisticated data pipeline that integrates de-identified molecular tests and clinical trial data, with the flexibility to incorporate additional datasets based on transplant centers' requests. VANTx employs advanced machine-learning techniques, such as the Llama 3 foundational model, to deliver predictive insights essential for kidney, heart, lung, and liver transplant research.

The platform not only aids in generating critical analyses but also seeks to improve transplant care by addressing significant research interests like delayed graft function and cancer risk. Currently available to transplant centers through consultations with CareDx’s team, VANTx will soon offer self-service access to clinicians later in 2026, marking a significant step forward in leveraging AI for transplant patient care.

CareDx continues to position itself as the leader in genomics-based information for transplant patients, dedicated to advancing organ health and improving outcomes globally.

MWN-AI** Analysis

CareDx, Inc. (Nasdaq: CDNA) is making significant strides in the field of precision medicine by launching VANTx™, an AI-powered clinical data and analytics platform tailored for the transplant sector. This innovative platform aims to transform the management of complex transplant data into actionable insights, thus revolutionizing clinical research and real-world evidence development.

Investors should pay close attention to the potential impact of VANTx on CareDx’s growth trajectory. By harnessing a robust, cloud-native environment that incorporates advanced AI techniques and a continuous data pipeline, CareDx is positioning itself at the forefront of the transplant market. The platform’s ability to perform real-time cohort analysis and generate insights can enhance treatment protocols and clinical trial designs, ultimately leading to improved patient outcomes.

The launch, announced at the Precision Medicine World Conference, showcases CareDx's commitment to innovation. The inclusion of predictive models focusing on critical areas such as delayed graft function and rejection risks highlights the platform's utility in addressing significant clinical challenges. This positions CareDx as not only a product provider but also a vital partner for transplant centers and pharmaceutical firms seeking to refine treatment methodologies.

Furthermore, as healthcare continues to pivot towards technology-driven solutions, CareDx’s investments in AI over the past 24 months could yield substantial returns. The anticipated self-service access for clinicians later in 2026 may also drive wider adoption, leading to possible revenue growth.

However, investors should remain cautious of the inherent risks. CareDx's forward-looking statements indicate potential challenges in realizing the expected benefits of VANTx, underscoring the necessity of vigilant monitoring of financial performance and market adoption.

In summary, while CareDx is well-positioned for growth with VANTx, investors should approach with a balanced perspective, considering both the opportunities and risks involved in this innovative venture.

**MWN-AI Summary and Analysis is based on asking OpenAI to summarize and analyze this news release.

Source: Business Wire

First-of-its-kind, cloud-native AI platform for transplant program cohort analysis, clinical research, and real-world evidence generation announced at the 2026 Precision Medicine World Conference

CareDx, Inc. (Nasdaq: CDNA) — The Transplant Company™, a leading precision medicine company focused on the discovery, development, and commercialization of clinically differentiated, high?value healthcare solutions for transplant patients and caregivers, today announced the launch of VANTx™, an AI?powered, cloud?native clinical data and analytics platform designed to transform complex transplant data into insights that support clinical research and real?world evidence development.

VANTx is designed for secure, scalable cohort analysis across longitudinal patient timelines that enables the evaluation of treatment trends, patient outcomes, and practice patterns. The platform is intended to support clinicians, transplant programs, and pharma partners in testing hypotheses to generate actionable findings for treatment protocol development, investigator-initiated studies, and clinical trial design.

Jing Huang, Chief Data and AI Officer of CareDx, will be introducing VANTx at the Precision Medicine World Conference (PMWC) in Silicon Valley, California, on March 5, 2026, during the session “Transforming Transplant Care Through AI: From Predictive Insights to Precision Decisions.” The presentation will take place as part of the “AI in Clinical Decision Support” track.

“As the market leader in transplant precision diagnostics and patient care solutions, we can help our transplant center partners generate actionable insights using LLMs and other models.” said Jing Huang, Chief Data and AI Officer at CareDx. “I joined CareDx to lead the development of the VANTx platform and to help transplant teams and researchers make sense of complex, longitudinal data in a way that is intuitive, clinically meaningful, and actionable. I am thrilled to see this vision and the investment we have made over the past 24 months in AI architecture starting to become a reality in support of transplant care globally.”

VANTx operates on a live data pipeline of CareDx’s continuously expanding, multidimensional data repository of de-identified molecular tests and clinical trial data, with the ability to incorporate additional data at the transplant center’s request including EMR, care quality, and remote patient monitoring data. VANTx receives real?time ingestion from laboratory and clinical data sources and is built on a Databricks environment that leverages the Llama 3 foundational model and other advanced machine-learning techniques optimized for structured clinical data. Additionally, VANTx will incorporate validated predictive and prognostic insights models from KOAR, SHORE, ALAMO, and MAPLE with the goal of supporting kidney, heart, lung, and liver transplant research, respectively. These models are intended to inform sub-analyses of predicted disease risk in areas of significant research interest to the clinical community such as delayed graft function, microvascular inflammation, antibody mediated rejection, cardiac allograft vasculopathy, and cancer risk.

VANTx is available to transplant centers through consultation with CareDx’s medical affairs team today, and the company intends to make it available through self-service permission-based access to clinicians later in 2026.

About CareDx

CareDx is a precision medicine company dedicated to improving outcomes for transplant patients and advancing organ health. The Company’s integrated solutions include non?invasive molecular testing for heart, kidney, and lung transplants; laboratory products; digital health technologies; and patient solutions that support care before and after transplant. CareDx is the leading provider of genomics?based information for transplant patients. For more information, please visit www.caredx.com .

Forward Looking Statements

This press release includes forward-looking statements related to CareDx including statements regarding the potential benefits and results that may be achieved with VANTx, AlloSure, AlloMap, and HeartCare. These forward-looking statements are based upon information that is currently available to CareDx and its current expectations, speak only as of the date hereof, and are subject to risks and uncertainties that could cause actual results to differ materially from those projected, including risks that CareDx does not realize the expected benefits of VANTx, AlloSure, AlloMap, and HeartCare, risks that the findings in the data may be inaccurate, general economic and market factors, and other risks discussed in CareDx’s filings with the Securities and Exchange Commission (the “SEC”), including, but not limited to, the Annual Report on Form 10-K for the fiscal year ended December 31, 2025 filed by CareDx with the SEC on February 25, 2026, and other reports that CareDx has filed with the SEC. Any of these may cause CareDx’s actual results, performance, or achievements to differ materially and adversely from those anticipated or implied by CareDx’s forward-looking statements. You are cautioned not to place undue reliance on these forward-looking statements. CareDx expressly disclaims any obligation, except as required by law, or undertaking to update or revise any such forward-looking statements, whether as a result of new information, future events or otherwise.

View source version on businesswire.com: https://www.businesswire.com/news/home/20260305457319/en/

CareDx, Inc.
Media
Natasha Moshirian Wagner
nwagner@CareDx.com

I nvestor Relations
Caroline Corner
investor@CareDx.com

FAQ**

How does CareDx Inc. CDNA plan to ensure data security and privacy while utilizing the VANTx platform for sensitive transplant patient information?

CareDx Inc. plans to ensure data security and privacy on the VANTx platform by implementing robust encryption, access controls, and compliance with regulatory standards such as HIPAA to protect sensitive transplant patient information.

What strategies will CareDx Inc. CDNA implement to encourage widespread adoption of the VANTx platform among transplant centers and clinical researchers?

CareDx Inc. plans to implement strategies such as targeted educational initiatives, strategic partnerships with key opinion leaders in transplantation, robust clinical data promotion, and streamlined user experience enhancements to promote widespread adoption of the VANTx platform.

Can you explain how the integration of the Llama 3 foundational model enhances the capabilities of the VANTx platform in analyzing transplant data for CareDx Inc. CDNA?

The integration of the Llama 3 foundational model enhances the VANTx platform's capabilities by leveraging advanced machine learning algorithms to improve data analysis accuracy and efficiency in transplant outcomes for CareDx Inc. CDNA.

What specific goals does CareDx Inc. CDNA have for VANTx regarding real-world evidence generation and its impact on clinical practice patterns in transplant care?

CareDx Inc. aims for VANTx to generate real-world evidence that enhances transplant care by improving clinical practice patterns, supporting early detection of transplant-related complications, and ultimately optimizing patient outcomes and resource utilization.

**MWN-AI FAQ is based on asking OpenAI questions about CareDx Inc. (NASDAQ: CDNA).

CareDx Inc.

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