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The Medicines Company (NASDAQ: MDCO ) announces positive results from a Phase 3 clinical trial, ORION-11 , evaluating twice-yearly dosing of inclisiran aimed at reducing LDL-C ("bad" cholesterol) in patients with atherosclerotic cardiovascular disease. More news on: The Medicines Compan...
ORION-11 study met all primary and secondary efficacy endpoints with efficacy consistent with Phase 1 and 2 studies Safety profile of inclisiran was at least as favorable as in ORION-1 Phase 2 and ORION-3 open-label extension studies Detailed data will be presented...
In terms of controlling what they can control, I believe Alnylam Pharmaceuticals ( ALNY ) management is doing a good job. While there has certainly been criticism of the high cash burn and the large sums that the company spends on R&D, I believe funding a robust Phase III development pro...
This article is part of a series that provides an ongoing analysis of the changes made to David Einhorn's Greenlight Capital 13F portfolio on a quarterly basis. It is based on Einhorn's regulatory 13F Form filed on 08/14/2019. Please visit our Tracking David Einhorn's Greenlight Capital Hol...
Paratek Pharmaceuticals ( PRTK ) reported earnings on Tuesday, August 6, with the stock trading up over 30% in response to the report and then running further throughout the rest of the week. I find the numbers from the launch of Nuzyra (omadacycline), however, to be less than encouraging. I...
Regeneron Pharmaceuticals (NASDAQ: REGN ) announces the successful outcome of a Phase 3 clinical trial, ELIPSE HoFH , evaluating evinacumab in patients with an inherited form of severely elevated levels of "bad" (LDL-C) cholesterol called homozygous familial hypercholesterolemia (HoFH). ...
I took interest in The Medicines Company ( MDCO ) as part of my research on Alnylam ( ALNY ), a potential Long-Term Growth Portfolio holding which has an economic interest in MDCO’s main asset inclisiran. The company is about to report inclisiran’s phase 3 topline results...
The Medicines Company (MDCO) Q2 2019 Earnings Conference Call July 24, 2019 08:30 AM ET Company Participants Krishna Gorti - Vice President, Investor Relations Mark Timney - Chief Executive Officer Christopher Visioli - Chief Financial Officer Peter Wijngaard - Chief Developmen...
- Sequential release of topline pivotal Phase 3 data readouts expected to start in second half of the third quarter - Independent Data Monitoring Committee recommends continuation of inclisiran Phase 3 clinical trials after seventh un-blinded data review - ORION-11 data expected ...
Biotech Pulse The first half of 2019 had a little bit of everything for biotechs. After a punishing close to last year, with the Nasdaq Biotechnology Index ( IBB ) down 10% for 2018, biotechs rebounded during the first quarter along with the broader market. However, the second quarter provid...
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The Medicines Company (the “Company”) today provided notice of a Make-Whole Fundamental Change to holders of its (i) 2.50% Convertible Senior Notes due 2022 (the “2022 Notes”), (ii) 2.75% Convertible Senior Notes due 2023 (the “2023 Notes”) and (ii) 3...
Shares of Meritor (NYSE: MTOR) , a global supplier of drivetrain, braking, and other aftermarket automotive solutions for vehicles, jumped as high as 16% Tuesday morning after markets digested the announcement that Meritor will join the S&P SmallCap 600 index. The announcement actually c...
NEW YORK , Dec. 30, 2019 /PRNewswire/ -- S&P Dow Jones Indices will make the following changes to the S&P SmallCap 600 effective prior to the open of trading on Monday, January 6 : NexPoint Residential Trust Inc. (NYSE: NXRT) will replace Avon Products Inc. (NYSE: AVP). Natura...