Harbor Capital Celebrates 3-Year Anniversary of Harbor Health Care ETF (MEDI)

A Compelling Active Strategy for a Health Care Allocation

Harbor Capital Advisors, Inc. (“Harbor”), a premier provider of investment solutions, is proud to celebrate the 3-year anniversary of the Harbor Health Care ETF (MEDI), an actively managed sector ETF subadvised by Westfield Capital Management Company, L.P. Since its inception in November 2022, MEDI has delivered strong performance and demonstrated its value as a differentiated health care allocation tool for advisors and institutions.

Built on Westfield’s deep expertise in Health Care investing MEDI offers a concentrated, high-conviction portfolio of 30–50 companies across the Health Care spectrum from biotechnology and life sciences to providers and pharmaceuticals. The ETF seeks long-term capital growth by investing in quality businesses with innovative products and services, guided by disciplined valuation criteria.

“MEDI is a distinct solution for advisors seeking active exposure to the Health Care sector,” said Kristof Gleich, President and Chief Investment Officer of Harbor Capital. “We launched this ETF with a clear purpose: to harness Westfield’s deep sector knowledge while seeking to deliver alpha through thoughtful, bottom-up stock selection. Three years in, MEDI continues to exceed expectations, and we believe it remains a powerful tool for clients navigating a rapidly evolving Health Care landscape.”

Westfield’s portfolio managers, William Muggia and Matthew Renna, bring nearly five decades of combined experience and a long-standing commitment to Health Care investing. Their approach emphasizes post-proof-of-concept companies with multiple assets in development, aiming to mitigate risk while capturing upside in innovative sub-sectors like biotech, targeted oncology, gene therapy, and orphan diseases.

As the Health Care sector continues to benefit from structural tailwinds including aging populations and scientific breakthroughs—Harbor encourages advisors to consider MEDI when allocating for clients seeking growth potential, innovation, and active management in their portfolios.

Average Annual Returns (as of September 30, 2025)

*3-yr figures are as of November 17, 2025.
All other figures are annualized as of September 30, 2025.

The Harbor Health Care ETF Gross Expense Ratio is 0.80%.

Performance data shown represents past performance and is no guarantee of future results. Past performance is net of management fees and expenses and reflects reinvested dividends and distributions. Past performance reflects the beneficial effect of any expense waivers or reimbursements, without which returns would have been lower. Investment returns and principal value will fluctuate and when redeemed may be worth more or less than their original cost. Returns for periods less than one year are not annualized. Current performance may be higher or lower and is available through the most recent month end at harborcapital.com or by calling 800-422-1050.

For more information about MEDI and Harbor’s suite of ETFs, visit harborcapital.com .

About Harbor Capital

Harbor Capital Advisors is an asset manager with AUM of $67.6 billion as of September 30, 2025, and is known for prudently curating innovative investment strategies from boutique managers from around the globe. Advisors looking for differentiated investment options for their clients’ portfolios often connect with our obsession to find what we believe are bold solutions that have the potential to produce compelling risk-adjusted returns. For more information, visit www.harborcapital.com .

Investors should carefully consider the investment objectives, risks, charges, and expenses of a Harbor fund before investing. To obtain a summary prospectus or prospectus for this and other information, visit harborcapital.com or call 800-422-1050. Read it carefully before investing.

All investments involve risk including the possible loss of principal.

Unlike mutual funds, ETFs may trade at a premium or discount to their net asset value.

Shares are bought and sold at market price not net asset value (NAV). Market price returns are based upon the closing composite market price and do not represent the returns you would receive if you traded shares at other times.

There is no guarantee that the investment objective of the Fund will be achieved. Stock markets are volatile and equity values can decline significantly in response to adverse issuer, political, regulatory, market and economic conditions. Since the Fund may hold foreign securities , it may be subject to greater risks than funds invested only in the U.S. These risks are more severe for securities of issuers in emerging market regions. Foreign currencies can decline in value and can adversely affect the dollar value of the fund. Since the Fund typically invests in a limited number of companies , an adverse event affecting a particular company may hurt the Fund's performance more than if it had invested in a larger number of companies.

Health Care Industry Risk: Because the Fund seeks to invest all, or substantially all, of its assets in the health care industry, the value of its shares will depend on the general condition of the that industry. The health care industry may be affected by any number of factors, including, but not limited to, lapsing patent protection, industry innovation, extensive government regulation, restrictions on government reimbursement for medical expenses, research and development costs, limited product lines, product liability litigation, an increased emphasis on outpatient services, and competitive forces. Authorized Participant Concentration/Trading Risk: Only authorized participants ("APs") may engage in creation or redemption transactions directly with the Fund. The Fund is classified as non?diversified, a non?diversified Fund may invest a greater percentage of its assets in securities of a single issuer, and/or invest in a relatively small number of issuers, it is more susceptible to risks associated with a single economic, political or regulatory occurrence than a more diversified portfolio. Small and Mid Cap Risk: The Fund's performance may be more volatile because it may invest in issuers that are smaller companies.
The views expressed herein may not be reflective of current opinions, are subject to change without prior notice, and should not be considered investment advice.

The Russell 3000® Growth Health Care Index is an unmanaged index generally representative of companies involved in medical services or health care in the Russell 3000 Index, which is comprised of the 3,000 largest U.S. companies as determined by total market capitalization. This unmanaged index does not reflect fees and expenses and is not available for direct investment.

The views expressed herein may not be reflective of current opinions, are subject to change without prior notice, and should not be considered investment advice.

Diversification cannot assure a profit nor protect against a loss.

Foreside Fund Services, LLC is the Distributor of the Harbor ETFs.

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