STRATA Skin Sciences Highlights Meta-Analysis Confirming Clinical Efficacy of 308 nm Excimer Laser for Plaque Psoriasis
MWN-AI** Summary
STRATA Skin Sciences, Inc. (NASDAQ: SSKN) has announced significant findings from a meta-analysis confirming the clinical efficacy of the 308 nm Excimer laser for treating plaque psoriasis. Published in the Journal of Drugs in Dermatology, the systematic review was conducted by researchers from Georgetown University and MedStar Washington Hospital Center, examining previous clinical trials where patients underwent treatment with the Excimer laser.
The analysis aggregated data from multiple studies where patients received treatment twice weekly for a minimum of ten sessions using the Psoriasis Area and Severity Index (PASI) for outcome measurement. Remarkable reductions in PASI scores were observed, with results indicating improvements of approximately 56% to 85% across different trials. Notably, patients typically achieved these outcomes within 10 to 14 treatments over a 5 to 7 week period, highlighting the efficiency of the Excimer laser therapy.
Central to the treatment’s success was the use of minimal erythema dose (MED)-guided dosing, allowing for tailored delivery of high-fluence 308 nm UVB directly to affected areas while avoiding surrounding healthy skin. This targeted approach is enhanced by STRATA’s advanced XTRAC technology, which can effectively deliver higher fluences, exceeding those in traditional UVB phototherapies.
CEO Dr. Dolev Rafaeli emphasized the importance of the findings, reinforcing that precision-targeted treatment with MED-guided Excimer laser therapy offers a significant therapeutic advantage for effective psoriasis management. The results advocate for the continued integration of these laser strategies into dermatological practices, further establishing STRATA Skin Sciences' commitment to advancing innovative skin therapies.
MWN-AI** Analysis
STRATA Skin Sciences (NASDAQ: SSKN) has recently garnered positive attention following the publication of a meta-analysis confirming the efficacy of its 308 nm Excimer laser for treating plaque psoriasis. This systematic review published in the *Journal of Drugs in Dermatology* showcased impressive reductions in Psoriasis Area and Severity Index (PASI) scores across various clinical studies. For investors, this is a pivotal moment, suggesting a potential uptick in product demand and market share.
Given STRATA's solid clinical evidence, the company is positioned well in the dermatological treatment landscape. The 308 nm Excimer laser not only provides significant improvements in PASI scores but also highlights the advantages of MED-guided dosing, which offers personalized treatment options that may draw more practitioners to adopt these technologies in their practices. The focus on high-fluence precision, which allows for effective treatment with minimal skin damage, sets STRATA apart from competitors offering traditional broadband UVB therapies.
From a financial perspective, STRATA's innovative partnership approach, where practices pay per treatment rather than for equipment outright, presents a scalable model that could expand its reach into more dermatology clinics, thus increasing its revenue streams. The success of the XTRAC® technology in delivering optimized doses efficiently stands to benefit both patients and practitioners.
However, potential investors should remain cautious regarding broader market adoption, as various factors—including physician training, patient acceptance, and health insurance reimbursement policies—could impact uptake. STRATA’s ongoing commitment to research and the refinement of its offerings signals that it is addressing these challenges proactively.
In conclusion, while STRATA Skin Sciences presents a compelling investment opportunity bolstered by recent clinical evidence and innovative business practices, all stakeholders should monitor market trends and regulatory environments closely to gauge future performance.
**MWN-AI Summary and Analysis is based on asking OpenAI to summarize and analyze this news release.
HORSHAM, Pa., Feb. 17, 2026 (GLOBE NEWSWIRE) -- STRATA Skin Sciences, Inc. (NASDAQ: SSKN), a medical technology company dedicated to developing, commercializing, and marketing innovative dermatologic treatments, today highlights findings from a February 2026 systematic review and meta-analysis confirming the clinical efficacy of 308 nm Excimer laser in plaque psoriasis. Published in the Journal of Drugs in Dermatology by investigators from Georgetown University School of Medicine and the Department of Dermatology at MedStar Washington Hospital Center, the analysis evaluated clinical trials assessing the efficacy of the 308 nm excimer laser for plaque psoriasis. Across the included studies, patients were treated twice weekly for a minimum of 10 sessions, with outcomes measured using the Psoriasis Area and Severity Index (PASI). The study by Gratz, Ben, et al., titled, "Excimer Laser for Plaque Psoriasis: A Systematic Review and Meta-analysis" was published in the Journal of Drugs in Dermatology (JDD 25.2 (2026): e36-e37.).
“This meta-analysis reinforces what dermatologists have observed clinically — that properly calibrated, MED-guided Excimer Laser therapy provides effective, targeted treatment for plaque psoriasis,” said Dr. Dolev Rafaeli, STRATA Skin Sciences Chief Executive Officer. “Enabling the delivery of high-fluence 308nm UVB precisely to affected plaques while sparing surrounding healthy skin represents a meaningful therapeutic advantage.”
Significant PASI Improvements Across Studies
The meta-analysis demonstrated substantial and statistically significant reductions in PASI scores through review of previously published studies, including:
- Tang et al. (n=32): PASI improved from 11.47 to 5.08 (~56% reduction)
- He et al. (n=40): PASI improved from 14.73 to 2.42 (~84% reduction)
- Gerber et al. (n=100): PASI improved from 13.70 to 2.10 (~85% reduction)
- Dong et al. (n=20): PASI improved from 12.02 to 4.09 (~66% reduction)
Patients typically achieved these outcomes within 10–14 treatments over approximately 5–7 weeks, underscoring the efficiency of targeted excimer laser protocols.
MED-Guided Dosing and Targeted Fluence Delivery
A key focus of the publication was the role of minimal erythema dose (MED)-guided dosing, a patient-specific calibration method that determines the lowest UVB fluence producing visible erythema at 24 hours.
Across the studies reviewed, treatment fluences generally ranged from approximately 200–600 mJ/cm² per session (1–3× MED), (and in some protocols, up to 1,200 mJ/cm² total fluence per session when higher MED multiples are used). These energy levels are considered higher than typical starting doses in conventional broadband or narrowband UVB phototherapy, reflecting the targeted, lesion-directed dosing inherent in excimer laser protocols.
Prior excimer laser studies (see, e.g. Al-Mutairi N, Al-Haddad A. “Targeted phototherapy using 308 nm Xecl monochromatic excimer laser for psoriasis at difficult to treat sites,” Lasers Med Sci. 2013 Jul;28(4):1119-24. doi: 10.1007/s10103-012-1210-4. Epub 2012 Sep 28. PMID: 23053247) found higher MEDs in certain patient populations, e.g., a mean MED of ~383 mJ/cm² for scalp psoriasis and ~415 mJ/cm² for palmoplantar psoriasis (with ranges up to ~650–950 mJ/cm²), indicating anatomical and individual variability and pointing to a need for high fluence which can only be delivered with energy enabled devices.
STRATA’s latest high-power XTRAC® technology models enable practices to deliver these optimized targeted doses efficiently, supporting short treatment times for patients while maintaining favorable practice economics.
Clinical Significance
The data confirm that MED-based excimer laser dosing consistently produces clinically meaningful and statistically significant PASI reductions.
The publication, authored by established dermatology researchers from Georgetown University and MedStar Washington Hospital Center, highlights continued academic interest in refining targeted UVB strategies within mainstream clinical dermatology.
Conclusion
The February 2026 meta-analysis confirms that 308 nm Excimer Laser therapy, reliably produces significant improvement in plaque psoriasis.
STRATA Skin Sciences remains committed to advancing clinical evidence-based dermatologic therapies that improve outcomes for patients living with chronic inflammatory skin diseases.
About STRATA Skin Sciences, Inc.
STRATA Skin Sciences is a medical technology company dedicated to developing, commercializing, and marketing innovative products for the in-office treatment of various dermatologic conditions, such as psoriasis, vitiligo, and acne. Its products include the XTRAC® excimer laser, VTRAC® lamp systems, and the TheraClear®X Acne Therapy System.
STRATA is proud to offer these exciting technologies in the U.S. through its unique Partnership Program. STRATA’s popular partnership approach includes a fee per treatment cost structure versus an equipment purchase, installation and use of the device, on-site training for practice personnel, service and maintenance of the equipment, dedicated account and customer service associates, and co-op advertising support to help raise awareness and promote the program within the practice.
Safe Harbor
This press release includes "forward-looking statements" within the meaning of the Securities Litigation Reform Act of 1995. These statements include but are not limited to the Company’s plans, objectives, expectations and intentions and may contain words such as “will,” “may,” “seeks,” and “expects,” that suggest future events or trends. More specific risks and uncertainties are set forth in the Company’s SEC reports on Forms 10-Q and 10-K. Given such uncertainties, any or all these forward-looking statements may prove to be incorrect or unreliable. The statements in this press release are made as of the date of this press release, even if subsequently made available by the Company on its website or otherwise. The Company does not undertake any obligation to update or revise these statements to reflect events or circumstances occurring after the date of this press release. The Company urges investors to carefully review its SEC disclosures available at www.sec.gov and www.strataskinsciences.com.
Investor Contact:
CORE IR
516-222-2560
IR@strataskin.com
FAQ**
How does Strata Skin Sciences Inc. SSKN plan to leverage the findings from the recent meta-analysis on 308 nm Excimer laser therapy to expand its market share in dermatologic treatments?
What are the expected financial implications for Strata Skin Sciences Inc. SSKN following the publication of positive meta-analysis results on excimer laser efficacy for plaque psoriasis?
Can Strata Skin Sciences Inc. SSKN provide insights into potential partnerships or collaborations that might arise due to the positive clinical data on its XTRAC® technology?
What measures is Strata Skin Sciences Inc. SSKN taking to ensure consistent training and support for practitioners utilizing their excimer laser technology based on recent clinical findings?
**MWN-AI FAQ is based on asking OpenAI questions about Strata Skin Sciences Inc. (NASDAQ: SSKN).
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