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Shattuck Labs Announces Participation in Upcoming Piper Sandler Virtual Novel Targets in Immunology Symposium

MWN-AI** Summary

Shattuck Labs, Inc. (NASDAQ: STTK), a biotechnology company focused on developing therapies targeting tumor necrosis factor (TNF) superfamily receptors for inflammatory and immune-mediated conditions, announced its participation in the upcoming Piper Sandler Virtual Novel Targets in Immunology Symposium, scheduled for February 12-13, 2026. Company executives, including CEO Taylor Schreiber, CFO Andrew R. Neill, and VP of Clinical Development Michael Choi, will engage in a fireside chat during the conference, set for February 12 at 2:00 PM ET.

The event will serve as a platform for Shattuck Labs to discuss its innovative approach and showcase its clinical pipeline, particularly focusing on SL-325, a potential first-in-class antibody targeting the Death Receptor 3 (DR3). This promising drug aims for an effective and sustained blockade of the DR3/TL1A pathway, with Shattuck’s preclinical research indicating superior efficacy compared to existing TL1A antibodies. SL-325, currently undergoing Phase 1 clinical trials, is an Fc-silenced humanized immunoglobulin G monoclonal antibody that has demonstrated a favorable safety profile in non-human primates.

Shattuck Labs is dedicated to finding solutions for conditions such as inflammatory bowel disease (IBD) and has established expertise in protein engineering, harnessing the development of novel TNF receptor therapeutics. This fireside chat at the Piper Sandler conference presents a critical opportunity for the company to connect with investors and stakeholders about its pioneering research and future directions in immunology.

A replay of the fireside chat will be made available on Shattuck's website starting February 12, 2026, at 2:00 PM ET, and will remain accessible for 30 days. For more information, stakeholders can visit www.ShattuckLabs.com.

MWN-AI** Analysis

Shattuck Labs, Inc. (NASDAQ: STTK) is at a pivotal point in its development of novel therapeutics designed to target inflammatory and immune-mediated diseases, specifically through its promising lead candidate, SL-325. As the company prepares for its participation in the Piper Sandler Virtual Novel Targets in Immunology Symposium on February 12-13, 2026, investors should note key developments impacting the stock's trajectory.

The focus on SL-325, a first-in-class Death Receptor 3 (DR3) blocking antibody, is particularly noteworthy. The data from preclinical studies suggest its potential for superior efficacy compared to current TL1A antibodies, positioning it uniquely in a crowded market. Given the increasing prevalence of inflammatory conditions such as inflammatory bowel disease (IBD), the demand for innovative treatments is expected to grow. This provides Shattuck Labs with a strategic window to capitalize on its advancements.

Investors should pay close attention to the upcoming presentation, where company executives will likely discuss further insights into SL-325's clinical trial results and the strategic direction of the company. The projected safety profile observed in non-human primates offers an encouraging outlook for patient applications, which could propel the stock's performance should results from ongoing Phase 1 trials prove favorable.

Moreover, the biotechnology sector is characterized by volatility linked to clinical trial outcomes. Thus, while Shattuck Labs presents a compelling investment opportunity, it carries inherent risks associated with clinical-stage companies. Investors should carefully evaluate their risk tolerance and consider engaging in a diversified strategy to mitigate potential impacts from fluctuations in clinical advancements.

In summary, Shattuck Labs appears poised for growth in a vital therapeutic area within biotechnology. Attending the symposium could provide investors with valuable insights to make informed decisions, balancing the prospects of robust innovation against the inherent risks of the sector.

**MWN-AI Summary and Analysis is based on asking OpenAI to summarize and analyze this news release.

Source: GlobeNewswire

AUSTIN, TX and DURHAM, NC, Feb. 06, 2026 (GLOBE NEWSWIRE) -- Shattuck Labs, Inc. (Shattuck) (NASDAQ: STTK), a clinical-stage biotechnology company pioneering the development of novel therapeutics targeting tumor necrosis factor (TNF) superfamily receptors for the treatment of patients with inflammatory and immune-mediated diseases, today announced that company management will participate in a fireside chat at the Piper Sandler Virtual Novel Targets in Immunology Symposium, taking place February 12-13, 2026.

Conference Details

Conference: Piper Sandler Virtual Novel Targets in Immunology Symposium
Format: Fireside chat
Presenters: Taylor Schreiber, M.D., Ph.D., Chief Executive Officer, Andrew R. Neill, Chief Financial Officer, and Michael Choi, M.D., Vice President of Clinical Development
Presentation Date: February 12, 2026
Time: 2:00 PM ET
Webcast link: HERE

A replay of the prerecorded presentation from the Piper Sandler Virtual Novel Targets in Immunology Symposium fireside chat will be available on the Events and Presentations section of the Company’s website starting at 2:00 PM ET on Thursday, February 12, 2026. A replay of the webcast will be archived for up to 30 days following the presentation date.

About SL-325
SL-325 is a potential first-in-class Death Receptor 3 (DR3) blocking antibody designed to achieve a complete and durable blockade of the clinically validated DR3/TL1A pathway. Shattuck’s preclinical studies demonstrate high affinity binding and superior activity over TL1A antibodies and offer a data-driven rationale for targeting the TNF receptor, DR3, versus its ligand, TL1A. SL-325 is a fully Fc-silenced humanized immunoglobin G monoclonal antibody with a favorable safety profile in non-human primates, currently being evaluated in a Phase 1 clinical trial.

About Shattuck Labs, Inc.
Shattuck Labs, Inc. (Nasdaq: STTK) is a clinical-stage biotechnology company specializing in the development of potential treatments for inflammatory and immune-mediated diseases. The Company is developing a potentially first-in-class antibody for the treatment of inflammatory bowel disease (IBD) and other inflammatory and immune-mediated diseases. Shattuck’s expertise in protein engineering and the development of novel TNF receptor therapeutics come together in its lead program, SL-325, a potentially first-in-class DR3 antagonist antibody designed to achieve a more complete blockade of the clinically validated DR3/TL1A pathway. The Company has offices in both Austin, Texas and Durham, North Carolina. For more information, please visit:?www.ShattuckLabs.com.

Investor & Media Contact:
Andrew R. Neill
Chief Financial Officer
Shattuck Labs, Inc.
InvestorRelations@shattucklabs.com


FAQ**

How does Shattuck Labs Inc. STTK plan to leverage its presence in both Austin, TX, and Durham, NC, to enhance its clinical development and potential market reach for SL-325?

Shattuck Labs Inc. plans to utilize its dual locations in Austin, TX, and Durham, NC, by fostering collaboration with regional biotech hubs and leveraging diverse clinical expertise to enhance the development and market reach of SL-325.

Considering the biotechnology landscape in Austin, TX, and Durham, NC, how does Shattuck Labs Inc. STTK view competition and collaboration opportunities in these regions?

Shattuck Labs Inc. (STTK) sees competition as a driving force for innovation and emphasizes collaboration with local biotech firms and research institutions in Austin, TX, and Durham, NC, to enhance their therapeutic development and accelerate market entry.

What are the strategic advantages for Shattuck Labs Inc. STTK in hosting events like the Piper Sandler Virtual Novel Targets in Immunology Symposium from its offices in Austin, TX, and Durham, NC?

Hosting events like the Piper Sandler Virtual Novel Targets in Immunology Symposium allows Shattuck Labs Inc. to enhance its visibility in the biotech community, foster collaboration with key players, showcase its innovations, and attract potential investors, all while leveraging its dual-office presence.

How does Shattuck Labs Inc. STTK intend to capitalize on the increasing interest in immunology and inflammatory diseases, particularly with its advancements in SL-325?

Shattuck Labs Inc. (STTK) plans to leverage the growing focus on immunology and inflammatory diseases by advancing SL-325, an innovative therapeutic candidate designed to enhance immune response and target underlying mechanisms of diseases, aligning with market demand.

**MWN-AI FAQ is based on asking OpenAI questions about Shattuck Labs Inc. (NASDAQ: STTK).

Shattuck Labs Inc.

NASDAQ: STTK

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Biotechnology & Life Sciences
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