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Spyre Therapeutics Stock Surges This Past Year as $10.5 Million Buy Lifts Stake to $78 Million

Source: Motley Fool

2026-02-23 10:38:15 ET

Commodore Capital disclosed a buy of 400,161 shares of Spyre Therapeutics (NASDAQ:SYRE) , an estimated $10.46 million trade based on quarterly average pricing, per a February 17, 2026, SEC filing.

According to a February 17, 2026, SEC filing , Commodore Capital increased its position in Spyre Therapeutics by 400,161 shares during the fourth quarter. The estimated transaction value is $10.46 million, based on the mean unadjusted closing price for the period. The quarter-end value of the stake rose by $44.92 million, a figure that includes both share accumulation and stock price appreciation.

Spyre Therapeutics, Inc. is a biotechnology company focused on innovative antibody-based therapies for inflammatory bowel disease. With a pipeline of differentiated preclinical assets, the company leverages advanced biologic platforms to address unmet needs in ulcerative colitis and Crohn's disease. Its strategy centers on scientific innovation and targeted therapeutic development to establish a competitive position in the IBD treatment landscape.

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Spyre Therapeutics Inc.

NASDAQ: SYRE

SYRE Trading

1.62% G/L:

$40.73 Last:

195,554 Volume:

$40.92 Open:

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SYRE Latest News

February 21, 2026 04:31:10 am
Expected earnings - Spyre Therapeutics Inc.

SYRE Stock Data

$2,603,991,883
65,619,664
1.61%
44
N/A
Biotechnology & Life Sciences
Healthcare
US
Waltham

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