Trevi Therapeutics to Report Fourth Quarter and Year End 2025 Financial Results and Provide Business Updates on March 17, 2026
MWN-AI** Summary
Trevi Therapeutics, Inc. (Nasdaq: TRVI), a clinical-stage biopharmaceutical company based in New Haven, Connecticut, has announced a conference call and live audio webcast scheduled for March 17, 2026, at 4:30 p.m. ET. This event will detail the company’s financial results for the fourth quarter and the full year ended December 31, 2025. In addition to financial reporting, senior management will provide key business updates during the session, which can be accessed through the company's website.
Trevi Therapeutics is at the forefront of addressing significant unmet medical needs with its investigational therapy, Haduvio™ (oral nalbuphine ER). This treatment targets chronic cough associated with idiopathic pulmonary fibrosis (IPF), non-IPF interstitial lung disease (non-IPF ILD), and refractory chronic cough (RCC). Notably, Haduvio is the first investigational therapy to demonstrate a statistically significant reduction in cough frequency in clinical trials for both patients with chronic cough linked to IPF and those with RCC, marking a potential breakthrough in the management of these debilitating conditions.
Chronic cough considerably affects a substantial portion of patients with IPF and non-IPF ILD, with an estimated 100,000 U.S. patients suffering from uncontrolled coughing. Meanwhile, RCC impacts 2-3 million Americans, presenting a challenging situation as it persists beyond standard treatment for other conditions. Trevi's Haduvio works by interacting with kappa and mu opioid receptors, influencing the cough reflex both centrally and peripherally, presenting a new hope for those affected.
With no FDA-approved therapies currently available for these conditions, Trevi Therapeutics remains dedicated to advancing its innovative treatment options. For further details and updates, stakeholders can visit www.TreviTherapeutics.com or follow the company on social media platforms.
MWN-AI** Analysis
Trevi Therapeutics, Inc. (Nasdaq: TRVI) is on the verge of a significant milestone, as it prepares to report its fourth-quarter and year-end financial results for 2025 on March 17, 2026. Investors should closely monitor this event due to Trevi's focus on developing Haduvio™ (oral nalbuphine ER) for chronic cough related to idiopathic pulmonary fibrosis (IPF) and refractory chronic cough (RCC)—conditions with heightened unmet medical needs.
Haduvio presents a unique value proposition by being the first investigational therapy to demonstrate a statistically significant reduction in cough frequency in clinical trials. With around 150,000 IPF patients and 2-3 million RCC patients in the U.S., the company is tapping into a substantial market. The absence of FDA-approved therapies for these conditions could position Haduvio as a critical solution, making Trevi a potentially attractive investment opportunity if clinical and regulatory progress continues.
Investors should pay attention to not only Trevi's financial results but also any updates on Haduvio’s development and regulatory path. Given the company's focus on a high-need patient population, successful trials could likely translate into strong commercial prospects. Any positive updates regarding Haduvio's safety and efficacy, or even advancements towards regulatory approvals, could generate significant interest and upward momentum in TRVI's stock price.
Moreover, Trevi's approach, utilizing the dual mechanism of action (KAMA) through opioid receptors, showcases its innovation in treating a debilitating condition. As the chronic cough market remains largely underserved, Haduvio's success could lead to a potential restructuring in therapeutic approaches for this segment.
In conclusion, stakeholders should stay informed about the impending conference call, as strategic insights from management could illuminate Trevi's path forward, influencing investment decisions significantly in the near term.
**MWN-AI Summary and Analysis is based on asking OpenAI to summarize and analyze this news release.
NEW HAVEN, Conn., March 10, 2026 (GLOBE NEWSWIRE) -- Trevi Therapeutics, Inc. (Nasdaq: TRVI), a clinical-stage biopharmaceutical company developing the investigational therapy Haduvio™ (oral nalbuphine ER) for the treatment of chronic cough in patients with idiopathic pulmonary fibrosis (IPF), non-IPF interstitial lung disease (non-IPF ILD), and refractory chronic cough (RCC), today announced that senior management will host a conference call and live audio webcast on Tuesday, March 17, 2026, at 4:30 p.m. ET, to provide business updates and review the Company's financial results for the fourth quarter and year ended December 31, 2025.
Conference Call and Webcast
To register for the live conference call and webcast, please visit the ‘Investors & News’ section of the Company’s website or access directly at ir.trevitherapeutics.com/news-events/events. Please note for phone participants: Once registered, you will receive an email with unique call-in details. An archived replay of the webcast will also be available for 30 days on the Company's website following the event.
About Trevi Therapeutics, Inc.
Trevi Therapeutics, Inc. is a clinical-stage biopharmaceutical company developing the investigational therapy Haduvio™ (oral nalbuphine extended-release) for the treatment of chronic cough in patients with idiopathic pulmonary fibrosis (IPF), non-IPF interstitial lung disease (non-IPF ILD), and refractory chronic cough (RCC). Haduvio is the first and only investigational therapy to show a statistically-significant reduction in cough frequency in clinical trials across both patients with IPF chronic cough and in patients with RCC. Haduvio acts on the cough reflex arc both centrally and peripherally as a kappa agonist and a mu antagonist (KAMA), targeting opioid receptors that play a key role in controlling chronic cough. Nalbuphine is not currently scheduled by the U.S. Drug Enforcement Agency.
Chronic cough in patients with IPF and non-IPF ILD is a condition with high unmet need and no FDA-approved therapies. There are ~150,000 U.S. patients with IPF, and two-thirds of these patients are faced with uncontrolled chronic cough. Additionally, there are ~228,000 U.S. patients with non-IPF ILD, with 50-60% having uncontrolled chronic cough. The impact of chronic cough is significant, with patients coughing up to 1,500 times per day. This consistent cough, and any associated damage, may lead to a higher risk of morbidity and mortality, including worsening disease, a higher risk of progression, increased respiratory hospitalizations, and a decline in patients' quality of life.? ?
RCC is a condition with high unmet need and no FDA-approved therapies. RCC is defined as a persistent cough lasting >8?weeks despite treatment for an underlying condition (i.e., asthma, gastroesophageal reflux disease, non-asthmatic eosinophilic bronchitis, upper airway cough syndrome, or post-nasal drip) and includes unexplained chronic cough. There are ~2-3 million U.S. patients with RCC, and it is believed to be associated with cough reflex hypersensitivity involving both the central and peripheral nervous systems. RCC is highly debilitating and may impact patients physically, psychologically, and socially. ?
Trevi intends to propose Haduvio as the trade name for oral nalbuphine ER. Its safety and efficacy have not been evaluated by any regulatory authority.?
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For more information, visit?www.TreviTherapeutics.com?and follow Trevi on?X?(formerly Twitter) and?LinkedIn.?
Investor Contact??
Jonathan Carlson??
Trevi Therapeutics, Inc.??
(203) 654 3286??
IR@trevitx.com
Media Contact??
Rosalia Scampoli??
914-815-1465??
rscampoli@marketcompr.com? ?
FAQ**
What updates can investors expect from Trevi Therapeutics Inc. (TRVI) during the conference call on March 17, 2026, regarding the progress of Haduvio™ for chronic cough treatments?
How will Trevi Therapeutics Inc. (TRVI) address the significant unmet need for patients with chronic cough associated with idiopathic pulmonary fibrosis and non-IPF ILD in its upcoming financial results discussion?
What are the key differentiators of Haduvio™ that Trevi Therapeutics Inc. (TRVI) plans to highlight in the context of its recent clinical trial results for chronic cough treatments?
Can Trevi Therapeutics Inc. (TRVI) provide insights on the market potential and future plans for the commercialization of Haduvio™ as a treatment for refractory chronic cough during the upcoming conference call?
**MWN-AI FAQ is based on asking OpenAI questions about Trevi Therapeutics Inc. (NASDAQ: TRVI).
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