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Xenon Pharmaceuticals Announces Pricing of Upsized $650.0 Million Public Offering

MWN-AI** Summary

Xenon Pharmaceuticals Inc. (Nasdaq: XENE), a biopharmaceutical company concentrating on neuroscience, has announced the pricing of its upsized public offering aimed at raising approximately $650 million. This offering entails the sale of 10,526,317 common shares at $57.00 per share, and pre-funded warrants at $56.9999 each, designed for certain investors who prefer not to purchase common shares directly. The offering, which is set to close around March 12, 2026, is contingent upon standard closing conditions being met.

The company has also granted its underwriters a 30-day option to acquire an additional 1,710,526 common shares at the public offering price, excluding any underwriting discounts and commissions. Key investment banks including J.P. Morgan, Jefferies, TD Cowen, Stifel, RBC Capital Markets, and William Blair are acting as joint book-running managers for the offering, with Baird serving as lead manager.

Xenon operates using an automatically effective shelf registration statement filed with the SEC, allowing them the flexibility to capitalize on market conditions. The pre-offering and final prospectus supplements, which provide detailed information and terms of the offering, are publicly accessible through the SEC’s website and via specified investment banks.

Xenon is engaged in the development of novel therapeutics, particularly its lead candidate, azetukalner, which is in Phase 3 trials for conditions such as epilepsy, major depressive disorder, and bipolar depression, as well as early-stage programs targeting pain treatment. The company maintains offices in Vancouver and Boston, and is actively advancing its clinical and preclinical pipelines to deliver impactful therapies to patients.

MWN-AI** Analysis

Xenon Pharmaceuticals Inc. (Nasdaq: XENE) recently announced the pricing of an upsized public offering, raising approximately $650 million through the sale of 10.5 million common shares at $57.00 each. This offering highlights the company’s strategic drive to strengthen its financial position, particularly as it pursues the development of innovative neurology-focused therapies, including its lead candidate azetukalner, which targets conditions such as epilepsy and major depressive disorder.

From an investment perspective, this capital infusion could bolster Xenon's development pipeline and support ongoing clinical trials. Given the growing demand for effective treatments in neuroscience, particularly for unmet medical needs, investors may find the stock appealing, especially as it progresses into higher phases of clinical development.

Investors should, however, assess the associated risks. Biopharma investments are significantly influenced by clinical trial outcomes, regulatory approvals, and market competition. As such, while the immediate financial outlook appears optimized by this public offering, the company's long-term success hinges on the efficacy of its drug candidates and their acceptance in the market.

Moreover, the upsized nature of the offering suggests strong institutional interest, indicative of confidence in Xenon's development strategy. This provides an additional layer of optimism for retail investors; however, the market's reaction to the offering will be crucial. If stock prices show volatility or decline post-offering, investors may encounter an attractive entry point.

In summary, while the recent capital raise should enhance Xenon's operational capabilities and potentially accelerate growth, investors must remain cognizant of the inherent risks in biotech investments. Maintaining a diversified portfolio and conducting thorough due diligence will be vital for those considering an investment in Xenon Pharmaceuticals.

**MWN-AI Summary and Analysis is based on asking OpenAI to summarize and analyze this news release.

Source: GlobeNewswire

VANCOUVER, British Columbia and BOSTON, March 10, 2026 (GLOBE NEWSWIRE) -- Xenon Pharmaceuticals Inc. (Nasdaq: XENE), a neuroscience-focused biopharmaceutical company dedicated to drug discovery, clinical development and commercialization of life-changing therapeutics for patients in need, today announced the pricing of its upsized underwritten public offering of 10,526,317 common shares and, in lieu of common shares to certain investors, pre-funded warrants to purchase up to 877,194 common shares pursuant to its existing shelf registration statement. The common shares are being offered at a public offering price of $57.00 per common share and the pre-funded warrants are being offered at a price of $56.9999 per pre-funded warrant. The gross proceeds to Xenon from the offering, before deducting underwriting discounts and commissions and other offering expenses payable by Xenon, are expected to be approximately $650.0 million. In addition, Xenon has granted to the underwriters of the offering an option for a period of 30 days to purchase up to an additional 1,710,526 common shares at the public offering price, less the underwriting discounts and commissions. The offering is expected to close on or about March 12, 2026, subject to the satisfaction of customary closing conditions.

J.P. Morgan, Jefferies, TD Cowen, Stifel, RBC Capital Markets, and William Blair are acting as joint book-running managers for the offering. Baird is acting as lead manager for the offering.

An automatically effective shelf registration statement relating to the securities offered in the public offering described above was filed with the Securities and Exchange Commission (the “SEC”) on August 9, 2024. The offering is being made only by means of a written prospectus and prospectus supplement that form a part of the registration statement. A preliminary prospectus supplement and accompanying prospectus relating to the offering have been filed with the SEC and are available on the SEC’s website at www.sec.gov. A final prospectus supplement and accompanying prospectus will be filed with the SEC. Copies of the final prospectus supplement and the accompanying prospectus, when available, may also be obtained by contacting J.P. Morgan Securities LLC, c/o Broadridge Financial Solutions, 1155 Long Island Avenue, Edgewood, NY 11717 or by email at prospectus-eq_fi@jpmchase.com and postsalemanualrequests@broadridge.com; Jefferies LLC, Attention: Equity Syndicate Prospectus Department, 520 Madison Avenue New York, NY 10022, by telephone at (877) 821-7388 or by email at Prospectus_Department@Jefferies.com; TD Securities (USA) LLC, c/o Broadridge Financial Solutions, 1155 Long Island Avenue, Edgewood, NY 11717 or by email at TDManualrequest@broadridge.com; Stifel, Nicolaus & Company, Incorporated, Attention: Syndicate, One Montgomery Street, Suite 3700, San Francisco, CA 94104, telephone: (415) 364-2720 or by emailing syndprospectus@stifel.com; RBC Capital Markets, LLC, Attention: Equity Capital Markets, 200 Vesey Street, New York, NY 10281, by telephone at (877) 822-4089, or by email at equityprospectus@rbccm.com; or William Blair & Company, L.L.C., Attention: Prospectus Department, 150 North Riverside Plaza, Chicago, Illinois 60606, by telephone at (800) 621-0687 or by email at prospectus@williamblair.com.

No securities are being offered or sold, directly or indirectly, in Canada or to any resident of Canada.

This press release shall not constitute an offer to sell or the solicitation of an offer to buy the securities being offered, nor shall there be any sale of the securities being offered in any state or other jurisdiction in which such offer, solicitation or sale would be unlawful prior to the registration or qualification under the securities laws of any such state or other jurisdiction.

Safe Harbor Statement
This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 and the Private Securities Litigation Reform Act of 1995 and Canadian securities laws. These forward-looking statements are not based on historical fact and include statements regarding the anticipated closing of the public offering. These forward-looking statements are based on current assumptions that involve risks, uncertainties and other factors that may cause the actual results, events or developments to be materially different from those expressed or implied by such forward-looking statements. These risks and uncertainties, many of which are beyond our control, include, but are not limited to, uncertainties related to market conditions and the completion of the public offering on the anticipated terms or at all; the impact of unstable economic conditions in the general domestic and global economic markets; adverse conditions from geopolitical events; as well as the other risks identified in our filings with the SEC and the securities commissions in British Columbia, Alberta and Ontario. These forward-looking statements speak only as of the date hereof and we assume no obligation to update these forward-looking statements, and readers are cautioned not to place undue reliance on such forward-looking statements.

About Xenon Pharmaceuticals Inc.

Xenon Pharmaceuticals (Nasdaq: XENE) is a neuroscience-focused biopharmaceutical company dedicated to drug discovery, clinical development and commercialization of life-changing therapeutics for patients in need. Xenon’s lead molecule, azetukalner, is a novel, potent KV7 potassium channel opener in Phase 3 clinical trials for the treatment of epilepsy, major depressive disorder (MDD) and bipolar depression (BPD). Xenon is also advancing an early-stage portfolio of multiple promising potassium and sodium channel modulators, including KV7 and NaV1.7 programs in Phase 1 development for the potential treatment of pain. Xenon has offices in Vancouver, British Columbia, and Boston, Massachusetts.

Xenon and the Xenon logo are registered trademarks or trademarks of Xenon Pharmaceuticals Inc. in the US, Canada, and elsewhere. All other trademarks belong to their respective owner.

Investor Contact:
Tucker Kelly
Chief Financial Officer
Email: investors@xenon-pharma.com

Source: Xenon Pharmaceuticals Inc.


FAQ**

How does the ongoing clinical development of Xenon Pharmaceuticals Inc. (XENE) enhance the biotechnology landscape in both Vancouver, BC and Boston, MA, considering their respective biopharma ecosystems?

Xenon Pharmaceuticals Inc.'s ongoing clinical development enhances the biotechnology landscape in Vancouver, BC, and Boston, MA, by fostering innovation, attracting talent, and strengthening collaboration within their respective biopharma ecosystems, ultimately driving economic growth and scientific advancement.

What potential impact do the gross proceeds from Xenon Pharmaceuticals Inc. (XENE)'s public offering have on future investment opportunities in Vancouver and Boston's biotechnology sectors?

The gross proceeds from Xenon Pharmaceuticals Inc.'s public offering could enhance future investment opportunities in Vancouver and Boston's biotechnology sectors by attracting additional capital, fostering innovation, and increasing market confidence in biotech development.

How might the closing of Xenon Pharmaceuticals Inc. (XENE)'s public offering affect job growth and innovation in neuroscience within Vancouver and Boston by March 2026?

The closing of Xenon Pharmaceuticals Inc.'s public offering could hinder job growth and innovation in neuroscience in Vancouver and Boston by reducing funding for research initiatives and limiting the ability to attract top talent, potentially stalling advancements in the field by March 2026.

In what ways do the strategic locations of Xenon Pharmaceuticals Inc. (XENE) in Vancouver and Boston benefit its operations and market reach in the competitive biopharmaceutical industry?

Xenon Pharmaceuticals' strategic locations in Vancouver and Boston enhance its operations and market reach by leveraging Canada's biotech innovation ecosystem and Boston's access to top-tier talent, research institutions, and venture capital in the competitive biopharmaceutical landscape.

**MWN-AI FAQ is based on asking OpenAI questions about Xenon Pharmaceuticals Inc. (NASDAQ: XENE).

Xenon Pharmaceuticals Inc.

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