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State Street SPDR S&P Pharmaceuticals vs First Trust NYSE Arca Biotech: Which Is the Better ETF For Your Portfolio?

Source: Motley Fool

2026-06-04 13:33:26 ET

The State Street SPDR S&P Pharmaceuticals ETF (NYSEMKT:XPH) offers a lower-cost entry into the drug manufacturing space, while the First Trust NYSE Arca Biotechnology Index Fund (NYSEMKT:FBT) provides concentrated exposure to biotechnology.

Investors seeking healthcare exposure often choose between mature pharmaceutical giants and high-growth biotechnology firms. This comparison examines how these two funds approach their respective sub-sectors, balancing the established cash flows of pharmaceuticals with the research-driven potential and the higher concentration of biotech innovators that populate the healthcare landscape.

Beta measures price volatility relative to the S&P 500; beta is calculated from five-year monthly returns. The 1-yr return represents total return over the trailing 12 months. Dividend yield is the trailing-12-month distribution yield.

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State Street SPDR S&P Pharmaceuticals ETF

NASDAQ: XPH

XPH Trading

3.44% G/L:

$58.07 Last:

49,270 Volume:

$56.70 Open:

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$314,371,574
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