SNGX - Soligenix's SGX301 shows sustained benefit in late-stage lymphoma study
Additional data from Phase 3 Flash trial evaluating Soligenix's ([[SNGX]] +6.4%) SGX301 (synthetic hypericin) in patients with cutaneous T-cell lymphoma ((CTCL)), has reinforced positive primary endpoint treatment response demonstrated in treatment cycle 1, with further improved response rates in Cycle 3.49% of patients who received SGX301 for 18 weeks, demonstrated a 50% or greater reduction in their lesion score compared to 40% of patients demonstrating such a reduction after completing 12 weeks of SGX301 treatment in Cycle 2.Continued analysis showed that 12 weeks of treatment is equally effective on both patch (response 37%) and plaque (response 42%) lesions when compared to Cycle 1 placebo lesion responses.Soligenix previously announced the FLASH study achieved statistical significance in its primary endpoint over the first 6-week treatment cycle (Cycle 1).After the subsequent additional 6-week treatment in the Cycle 2, the response rate in patients receiving a total of 12 weeks treatment increased two and a
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Soligenix's SGX301 shows sustained benefit in late-stage lymphoma study