SOLANA BEACH, Calif., June 04, 2024 (GLOBE NEWSWIRE) -- Artelo Biosciences, Inc. (Nasdaq: ARTL), a clinical-stage pharmaceutical company focused on modulating lipid-signaling pathways to develop treatments for people living with cancer, pain, dermatologic and neurological conditions, today announced that Professor Saoirse O'Sullivan will be presenting new preclinical data on ART26.12 at the 57th Annual Scientific Meeting of the British Pain Society. The conference is being held from June 4-6, 2024, in Nottingham, UK.
The presentations, titled, "ART26.12, a Novel Fatty Acid-binding Protein 5 Inhibitor, shows Efficacy in Breast Cancer-Induced Bone Pain" and "The Effects of the Fatty Acid Binding Protein 5 Inhibitor ART26.12 in a Rat Model of Diabetic Neuropathy," highlight Artelo's Fatty Acid Binding Protein 5 (FABP5) inhibitor under development for painful peripheral neuropathies and various cancers. Specifically, effective doses and plasma exposures are consistent with previously published data of ART26.12 in oxaliplatin-induced peripheral neuropathy (https://www.jpain.org/article/S1526-5900(24)00345-6/fulltext).
Professor Saoirse O'Sullivan, Vice President of Translational Sciences at Artelo, said, "We are pleased to be presenting these preclinical studies which underscore the broad therapeutic potential of ART26.12. Importantly, the data shows that oral treatment with ART26.12 was effective at reducing pain induced by cancer as well as diabetes, demonstrating that inhibiting FABP5 is a promising non-opioid, non-steroidal treatment strategy for pain."
"We have now demonstrated that ART26.12 has an attractive safety profile and is effective in ...