PHILADELPHIA, March 05, 2024 (GLOBE NEWSWIRE) -- Century Therapeutics (NASDAQ:IPSC), an innovative biotechnology company developing induced pluripotent stem cell (iPSC)-derived cell therapies in immuno-oncology and autoimmune and inflammatory diseases, today announced that preclinical data from the Company's iPSC-derived cell therapy platform will be presented in six posters at the upcoming 2024 American Association for Cancer Research (AACR) Annual Meeting being held April 5-10, 2024, in San Diego, CA. The upcoming abstracts highlight the Company's end-to-end capabilities in iPSC reprogramming and differentiation, gene editing, protein engineering and computational biology. Additionally, the Company will share new preclinical data on additional Allo-Evasion™ edits that could further support Century's multi-dosing strategy.
Details of the poster presentations are as follows:
Abstract Number: 36
Title: The Discovery of A Novel CD19xCD22 Dual-Targeting CAR For The Development Of An iPSC-Derived Cell Therapy
Poster Board Number: 4
Session Title: Adoptive Cell Therapies 2: CAR-T Cells
Session Date: Sunday, April 7, 2024
Session Time: 1:30 PM - 5:00 PM PT
Abstract Number: 1320
Title: Engineered Expression Of HLA-E And HLA-G Protects iPSC-Derived Cells from Killing By Primary NK Cells
Poster Board Number: 3
Session Title: CAR-K, NK Engagers, and NK Modulators
Session Date: Monday, April 8, 2024
Session Time: 9:00 AM - 12:30 PM PT
Abstract Number: 3613
Title: Screening iPSC Lines for Optimal Characteristics of Differentiation into Immune Effector Cells for Clinical Programs
Poster Board Number: 19
Session Title: Adoptive Cellular Therapy 1
Session Date: Monday, April 8, 2024
Session Time: 1:30 PM - 5:00 PM PT
Abstract Number: 1916
Title: Discovery of a Novel Nectin4 iPSC-derived Cell Therapy for the Treatment of Solid Tumors
Poster Board Number: 27
Session Title: Antibody Drug Conjugates and Bispecific Antibodies
Session Date: Monday, April 8, 2024
Session Time: 9:00 AM - 12:30 PM PT
Abstract Number: 4009
Title: Discovery Of Inhibitory CAR Target DSG1 For Damping NECTIN4 On-Target Off-Tumor Toxicity in iPSC-Derived CAR-T Cell Therapy
Poster Board Number: Section 2, 18
Session Title: Adoptive Cell Therapies 3: CAR-T Cells
Session Date: Tuesday, April 9, 2024
Session Time: 9:00 AM -12:30 PM PT
Abstract Number: 6802
Title: CXCR4 Transgene Improves In Vivo Migration and Efficacy of Engineered ...