SAN FRANCISCO, Nov. 02, 2023 (GLOBE NEWSWIRE) -- Nurix Therapeutics, Inc. (NASDAQ:NRIX), a clinical stage biopharmaceutical company developing targeted protein modulation drugs designed to treat patients with hematologic malignancies and solid tumors, today announced that clinical data will be presented for its two BTK degrader programs, NX-5948 and NX-2127, in two posters at the 65th American Society of Hematology Annual Meeting and Exposition being held December 9-12, 2023, in San Diego, CA. Nurix will also present a trials in progress poster for its NX-1607 program.
Poster Presentation Details:
Title: Initial findings from first-in-human phase 1a/b study of NX-5948, a selective Bruton's tyrosine kinase (BTK) degrader, in patients with relapsed/refractory B cell malignancies
Authors: Emma Searle, Francesco Forconi, Kim Linton, Alexey Danilov, Pam McKay, David Lewis, Dima El-Sharkawi, Mary Gleeson, John Riches, Sarah G. Injac, Ted Shih, Srinand Nandakumar, May Tan, Ganesh Cherala, Erin Meredith, Graham P. Collinsa
Session Name: 626. Aggressive Lymphomas
Prospective Therapeutic Trials: Poster III
Session Date and Time: Monday, December 11, 2023, 6:00 PM - 8:00 PM PT
Publication Number: 4473
Title: A first-in-human phase 1 trial of NX-2127, a first-in-class Bruton's Tyrosine Kinase (BTK) dual-targeted protein degrader with immunomodulatory activity, in patients with relapsed/refractory B cell malignancies
Authors: Alexey Danilov, Michael Tees, Krish Patel, William Wierda, Manish R. Patel, Ian Flinn, Tahir Latif, Weiyun Ai, Meghan C. Thompson, Michael Wang, Clare Sun, Deborah M. Stephens, Michael Thirman, Melissa Gessner, Johannes Wolff, Amanda Schwab, May Tan, Daniel Chan, Erin Meredith, Adrian Wiestner
Session Name: 626. Aggressive Lymphomas
Prospective Therapeutic Trials: Poster III
Session Date and Time: Monday, December 11, 2023, 6:00 PM - 8:00 PM PT
Publication Number: 4463
Title: A First-in-Human Phase 1 Trial of NX-1607, a First-in-Class Oral CBL-B Inhibitor, in Patients with Advanced Malignancies Including DLBCL
Authors: Graham P. Collins, William Townsend, Ahmed Abdulgawad, Swathi Namburi, Anja Williams, Ana Filipa Palma Dos Reis, Matthew G. Krebs, Jeff Evans, Sarah P. Blagden, Ruth Plummer, Daniel Hochhauser, Adam Sharp, George Cole, Seema Rogers, Daniel Chan, Sarah Whelan, Dima El-Sharkawi
Session Name: 626. Aggressive Lymphomas
Prospective Therapeutic Trials: Poster III
Session Date and Time: Sunday, December 10, 2023, 6:00 PM - 8:00 PM PT
Publication Number: 3093
About NX-2127
NX-2127 is a novel bifunctional molecule that degrades BTK ...