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Compugen to Participate in Stifel 2025 Healthcare Conference

MWN-AI** Summary

Compugen Ltd. (Nasdaq: CGEN) is set to participate in the upcoming Stifel 2025 Healthcare Conference in New York City, where members of its management team will engage in a fireside chat. Scheduled for November 11, 2025, from 3:20 to 3:50 PM ET, the conversation aims to provide insights into the company's innovative approaches in the field of cancer immunotherapy. A live webcast of the event will be available on Compugen's Investor Relations webpage, along with a replay post-event.

As a clinical-stage company, Compugen specializes in cancer therapeutics, leveraging its advanced AI-driven computational discovery platform, Unigen™, to identify promising drug targets and biological pathways. Among its leading candidates are COM701, an anti-PVRIG antibody currently in Phase 1 trials, and COM902, which targets the TIGIT protein for treating solid tumors. Notably, the company’s technology has also contributed to the development of Rilvegostomig, a bispecific antibody in Phase 3 trials by AstraZeneca, and GS-0321 (previously known as COM503), a unique anti-IL-18 antibody being developed in collaboration with Gilead.

Compugen remains focused on expanding its therapeutic pipeline, which includes various early-stage immuno-oncology programs aimed at fostering new mechanisms for immune system activation against cancers. Headquartered in Israel, with an additional office in San Francisco, Compugen continues to grow its presence in the biotech space, listed on both Nasdaq and the Tel Aviv Stock Exchange under ticker CGEN.

For further information, interested parties can contact Yvonne Naughton, Ph.D., who heads Investor Relations and Corporate Communications at Compugen.

MWN-AI** Analysis

Compugen Ltd. (Nasdaq: CGEN) is strategically positioned in the clinical-stage cancer immunotherapy sector, actively leveraging its AI/ML-powered computational discovery platform, Unigen™, to identify innovative drug targets. With an upcoming participation at the Stifel 2025 Healthcare Conference, the company presents a unique opportunity for investors to understand its trajectory and innovations in immunotherapy.

Compugen's robust pipeline includes two proprietary product candidates in Phase 1 development: COM701, an anti-PVRIG antibody, and COM902, which targets TIGIT in solid tumors. Notably, the transition of COM902 to collaboration with AstraZeneca reflects the increasing validation of Compugen's technology and its potential for generating best-in-class therapies. The firm’s earlier-stage projects, including the highly promising GS-0321 (formerly COM503), target critical pathways in oncology, presenting multiple avenues for growth.

Investors should closely monitor the upcoming fireside chat for insights into the company's strategic direction, upcoming clinical milestones, and potential partnerships. These discussions will provide a clearer picture of the competitive landscape in cancer immunotherapy, helping to gauge whether Compugen can effectively navigate sector challenges.

Given the increasing investment in cancer therapies and the innovative approaches Compugen employs, its shares present an intriguing opportunity for growth-oriented portfolios. However, potential investors should be cautious; while promising, the clinical stage is fraught with uncertainties, and market reactions can be volatile based on trial outcomes and company announcements.

Considering Compugen’s significant milestones ahead, potential investors may find it valuable to assess the outcomes of ongoing trials and collaborations closely. As the healthcare landscape evolves, keeping abreast of Compugen's progress and prepared for any volatility will be key for those looking to engage with CGEN in their investment strategies.

**MWN-AI Summary and Analysis is based on asking OpenAI to summarize and analyze this news release.

Source: PR Newswire

PR Newswire

HOLON, Israel, Nov. 4, 2025 /PRNewswire/ -- Compugen Ltd. (Nasdaq: CGEN) (TASE: CGEN), a clinical-stage cancer immunotherapy company and a pioneer in predictive computational drug target discovery powered by AI/ML, today announced that Compugen management will participate in a fireside chat at the upcoming Stifel 2025 Healthcare Conference in New York City. The fireside chat will take place on Tuesday November 11, 2025, at 3:20-3:50 PM ET.

A live webcast will be accessible on the Investor Relations section of the Compugen website at www.cgen.com. A replay will also be available following the live event.

About Compugen

Compugen is a clinical-stage therapeutic discovery and development company utilizing its broadly applicable predictive AI/ML powered computational discovery platform (Unigen) to identify new drug targets and biological pathways for developing cancer immunotherapies. Compugen has two proprietary product candidates in Phase 1 development: COM701, a potential first-in-class anti-PVRIG antibody and COM902, a potential best-in-class antibody targeting TIGIT for the treatment of solid tumors. Rilvegostomig, a PD-1/TIGIT bispecific antibody where the TIGIT component is derived from Compugen's clinical stage anti-TIGIT antibody, COM902, is in Phase 3 development by AstraZeneca through a license agreement for the development of bispecific and multispecific antibodies. GS-0321 (previously COM503), a potential first-in-class, high affinity anti-IL-18 binding protein antibody, which is in Phase 1 development, is licensed to Gilead. In addition, the Company's therapeutic pipeline of early-stage immuno-oncology programs consists of research programs aiming to address new mechanisms to activate the immune system against cancer. Compugen is headquartered in Israel, with offices in San Francisco, CA. Compugen's shares are listed on Nasdaq and the Tel Aviv Stock Exchange under the ticker symbol CGEN.

Company Contact:
Yvonne Naughton, Ph.D.
Vice President, Head of Investor Relations and Corporate Communications
Email: ir@cgen.com
Tel: +1 (628) 241-0071 

SOURCE Compugen Ltd.

FAQ**

Can you discuss the progress and key milestones achieved in the development of COM701 and COM902, the two proprietary product candidates of Compugen Ltd. CGEN, during the past year?

In the past year, Compugen Ltd. achieved significant milestones with COM701, advancing to multiple clinical trials for cancer treatment, and COM902, which progressed through preclinical studies, positioning both candidates for further development and potential market entry.

How does the predictive AI/ML technology of Compugen Ltd. CGEN enhance your ability to discover new drug targets compared to traditional methods in cancer immunotherapy?

Compugen Ltd.'s predictive AI/ML technology enhances drug target discovery in cancer immunotherapy by leveraging advanced algorithms to analyze vast datasets and identify novel targets more efficiently and accurately than traditional methods.

Could you provide an update on the Phase 3 development of Rilvegostomig, particularly any collaboration insights with AstraZeneca and how it impacts Compugen Ltd. CGEN's overall strategy?

As of October 2023, Compugen Ltd. (CGEN) is advancing Rilvegostomig in Phase 3, with collaboration insights from AstraZeneca enhancing strategic positioning and potential market expansion for CGEN's immunotherapy portfolio.

What new opportunities are unfolding in your early-stage immuno-oncology programs and how does Compugen Ltd. CGEN plan to leverage them for future growth?

Compugen Ltd. (CGEN) plans to leverage new opportunities in early-stage immuno-oncology by advancing its innovative pipeline of immune checkpoint candidates and utilizing proprietary algorithms to identify novel targets, aiming to enhance therapeutic efficacy and market presence.

**MWN-AI FAQ is based on asking OpenAI questions about Compugen Ltd. (NASDAQ: CGEN).

Compugen Ltd.

NASDAQ: CGEN

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