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Compugen to Present Research at the Single Cell Genomics 2025 Conference

MWN-AI** Summary

Compugen Ltd. (Nasdaq: CGEN), a clinical-stage cancer immunotherapy company, has announced its participation in the Single Cell Genomics 2025 Conference, scheduled from September 15 to 17, 2025, in Stockholm, Sweden. The company will present a poster detailing its innovative research capabilities, focusing on the integration of machine learning and artificial intelligence in understanding complex cancer biology, which is crucial for drug discovery and therapeutic strategies.

The highlights of Compugen's presentation include a poster titled "Bin2Niche: A spatial transcriptomics framework reveals immune-defined epithelial niches in MSI colorectal cancer." This research will be presented by Dr. Roy Granit, Senior Director and Head of Computational Discovery at Compugen, on September 15 at 2:10 PM CET. The findings aim to shed light on the spatial context within cancer ecosystems, furthering the potential for targeted immunotherapies that could substantially benefit cancer patients.

Compugen utilizes its AI-powered Unigen™ platform for predictive computational discovery, which is integral in identifying new drug targets and biological pathways. Currently, the company has two proprietary products in Phase 1: COM701, an anti-PVRIG antibody, and COM902, an antibody targeting TIGIT intended for treating solid tumors. Additionally, the company’s partnerships include a Phase 3 bispecific antibody development with AstraZeneca and a Phase 1 anti-IL-18 binding protein antibody licensed to Gilead.

With its growing pipeline in immuno-oncology and a strong focus on utilizing advanced computational dynamics, Compugen continues to position itself as an innovator in the fight against cancer, highlighted by its upcoming contributions at the Single Cell Genomics conference. For more information, the poster will be accessible on Compugen's website post-presentation.

MWN-AI** Analysis

Compugen Ltd. (NASDAQ: CGEN) has announced it will present significant research at the upcoming Single Cell Genomics 2025 Conference in Stockholm, highlighting its innovative predictive computational discovery capabilities in oncology. This marks a pivotal moment for the company, as the focus on spatial transcriptomics to explore immune-defined epithelial niches in colorectal cancer could lead to advanced therapeutic strategies. Such advancements build on the company’s solid foundation in AI-powered drug target discovery, positioning it strongly within a competitive market.

Investors should be keenly aware of Compugen's pipeline, which includes two proprietary candidates in Phase 1—COM701, an anti-PVRIG antibody, and COM902, targeting TIGIT. These candidates are critical in driving potential breakthroughs in cancer immunotherapy. Additionally, Compugen has a collaboration with AstraZeneca regarding a bispecific antibody, Rilvegostomig, indicating strong partnerships that could enhance its market reach and valuation.

The company's AI and machine learning capabilities stand out in a rapidly evolving field, positioning it favorably against competitors. Given the increasing demand for innovative cancer therapies, coupled with the rich data expected from the conference presentation, there lies potential for a positive market response.

Current investors would do well to keep an eye on stock performance around key dates related to clinical trials and regulatory discussions, as successes in these areas could drive share prices upward. For potential investors, considering an entry point now could yield rewards, particularly if the research presented showcases significant advances or strong preliminary data.

In conclusion, with a strategic focus on integration of advanced computational methods, partnerships, and robust pipeline candidates, Compugen is poised for growth. Monitoring developments as they materialize will be key to capitalizing on opportunities within this dynamic sector.

**MWN-AI Summary and Analysis is based on asking OpenAI to summarize and analyze this news release.

Source: PR Newswire

PR Newswire

HOLON, ISRAEL , Sept. 8, 2025 /PRNewswire/ -- Compugen Ltd. (Nasdaq: CGEN) (TASE: CGEN) a clinical-stage cancer immunotherapy company and a pioneer in predictive computational target discovery, powered by AI/ML today announced it will present research at the Single Cell Genomics 2025 Conference taking place September 15-17, 2025 , in Stockholm, Sweden .

This research reflects Compugen's computational capabilities in understanding the spatial context of complex cancer biology that may inform drug discovery efforts and therapeutic strategies to potentially provide benefit to cancer patients.

Poster and short talk details:

Title: Bin2Niche: A spatial transcriptomics framework reveals immune-defined epithelial niches in MSI colorectal cancer
Presenting author: Roy Granit , Ph.D., Senior Director, Head of Computational Discovery, Compugen
Poster ID: P035
Date of presentation: September 15, 2025 , at 2:10 PM CET

Poster will be available in the publications section of Compugen's website, www.cgen.com , following presentation.

About Compugen

Compugen is a clinical-stage therapeutic discovery and development company utilizing its broadly applicable predictive AI/ML powered computational discovery platform (Unigen™) to identify new drug targets and biological pathways for developing cancer immunotherapies. Compugen has two proprietary product candidates in Phase 1 development: COM701, a potential first-in-class anti-PVRIG antibody and COM902, a potential best-in-class antibody targeting TIGIT for the treatment of solid tumors. Rilvegostomig, a PD-1/TIGIT bispecific antibody where the TIGIT component is derived from Compugen's clinical stage anti-TIGIT antibody, COM902, is in Phase 3 development by AstraZeneca through a license agreement for the development of bispecific and multispecific antibodies. GS-0321 (previously COM503), a potential first-in-class, high affinity anti-IL-18 binding protein antibody, which is in Phase 1 development is licensed to Gilead. In addition, the Company's therapeutic pipeline of early-stage immuno-oncology programs consists of research programs aiming to address new mechanisms to activate the immune system against cancer. Compugen is headquartered in Israel , with offices in San Francisco, CA. Compugen's shares are listed on Nasdaq and the Tel Aviv Stock Exchange under the ticker symbol CGEN.

Company contact:

Yvonne Naughton , Ph.D.
Vice President, Head of Investor Relations and Corporate Communications
Email: ir@cgen.com
Tel: +1 (628) 241-0071

SOURCE Compugen Ltd.

FAQ**

How does the research being presented by Compugen Ltd. CGEN at the Single Cell Genomics 2025 Conference enhance our understanding of immunotherapy approaches for colorectal cancer?

Compugen Ltd.'s research at the Single Cell Genomics 2025 Conference provides insights into the immune landscape of colorectal cancer, revealing novel biomarkers and potential therapeutic targets that could improve the efficacy of immunotherapy strategies.

What specific advancements has Compugen Ltd. CGEN made in its AI/ML-powered computational discovery platform that are reflected in the research to be presented at the conference?

Compugen Ltd. has enhanced its AI/ML-powered computational discovery platform by integrating advanced algorithms for more accurate target identification and novel drug candidates, as evidenced by promising research findings to be showcased at the upcoming conference.

Can you explain how the findings from Compugen Ltd. CGEN's Bin2Niche framework could impact future therapeutic strategies for cancer treatment?

The findings from Compugen Ltd.'s Bin2Niche framework could significantly impact future cancer therapeutic strategies by uncovering novel immune checkpoint targets and enhancing the precision of cancer immunotherapy through personalized treatment approaches.

What are Compugen Ltd. CGEN's next steps following the insights gained from this research at the conference, especially regarding the development of their proprietary product candidates?

Compugen Ltd. (CGEN) plans to leverage insights from the conference to enhance their proprietary product candidates' development strategies, focusing on optimizing clinical trials and exploring potential collaborations to accelerate innovation and market entry.

**MWN-AI FAQ is based on asking OpenAI questions about Compugen Ltd. (NASDAQ: CGEN).

Compugen Ltd.

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