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Align Technology Supports Landmark Swiss Epidemiological Study Led by University of Bern

MWN-AI** Summary

Align Technology, Inc. (NASDAQ: ALGN), renowned for its innovative dental solutions, has partnered with the University of Bern to support Switzerland’s first comprehensive oral health study, known as the Swiss Oral Health Study. Spearheaded by Professor Dr. Hendrik Meyer-Lückel, this pioneering initiative aims to gather data on the oral health of various age groups across six cantons, targeting children aged 6-12, adults aged 35-44, and seniors aged 65-74. The study, officially launched in August 2025, is set to analyze nearly 3,450 individuals by the end of 2027, focusing on trends such as childhood caries and establishing a baseline for future public health strategies.

A key component of this research is the use of Align’s advanced iTero Lumina™ intraoral scanner. The device features innovative capabilities including wider field view, enhanced capture distance, and real-time near-infrared imaging technology, which notably improves diagnostic accuracy. By facilitating efficient data collection, the iTero Lumina scanner will help researchers enhance oral health understanding and preventive care methodologies.

To facilitate the research, an Align-branded mobile dental van equipped with the iTero Lumina scanner will travel to schools and communities across Switzerland, allowing for on-site examinations and digital scans. This mobile facility is designed for high productivity and aims to promote accessibility to dental care.

Align Technology’s Simon Beard articulated the firm’s commitment to dental research through this collaboration, highlighting the potential for improved patient care driven by data. Prof. Dr. Meyer-Lückel echoed this sentiment, emphasizing the study’s impact on shaping future oral health initiatives. This collaboration exemplifies the fruitful synergy between industry advancements and academic research, promising significant contributions to the field of oral health.

MWN-AI** Analysis

Align Technology (NASDAQ: ALGN) is positioning itself strongly in the dental market by participating in the Swiss Oral Health Study, leveraging its advanced iTero Lumina™ intraoral scanner. This partnership with the University of Bern not only underscores Align's commitment to improving public health outcomes but also signifies potential growth opportunities for investors.

The iTero Lumina scanner's centrality in this landmark epidemiological study serves as a testament to its technological superiority, including features such as a larger field of view and enhanced diagnostic capabilities. As the study aims to gather extensive data from a diverse population across key age groups, the integration of iTero Lumina is expected to enhance data accuracy—this aligns perfectly with the increasing demand for precision in dental diagnostics.

Investors should note that Align's involvement in this study may lead to greater credibility and visibility in the public health sector, potentially attracting new partnerships and broadened market acceptance. As the research aims to establish baselines for future public health strategies, the insights gleaned from the iTero Lumina scans could open new avenues for Align's technology in preventive care and policy-making discussions.

Furthermore, as the market continues to evolve towards digital solutions in healthcare, Align’s robust product offerings—specifically the iTero Lumina and Invisalign systems—position it favorably against competitors. With a clear focus on enhancing patient experiences and improving clinical workflows, the company's advancements are likely to resonate well in a sector increasingly leaning toward innovation.

In conclusion, Align Technology stands at a critical juncture with its involvement in the Swiss Oral Health Study, which not only enhances their reputation but could drive future revenue growth. Investors should monitor this collaboration closely as it may signify a pivotal moment in Align's trajectory in digital dentistry.

**MWN-AI Summary and Analysis is based on asking OpenAI to summarize and analyze this news release.

Source: Business Wire

iTero Lumina™ intraoral scanner has a central role in the study’s oral health data collection

Align Technology, Inc. (NASDAQ: ALGN) a leading global medical device company that designs, manufactures, and sells the Invisalign ® System of clear aligners, iTero™ intraoral scanners, and exocad™ CAD/CAM software for digital orthodontics and restorative dentistry, today announced its collaboration with the University of Bern on Switzerland’s first Swiss Oral Health Study – an epidemiological initiative led by Professor Dr. Hendrik Meyer-Lückel, director of the Clinic for Conservative, Preventive, and Pediatric Dentistry at the University of Bern.

Launched in August 2025, this study marks a significant milestone in Swiss dental research. It is the first large-scale, representative oral health study in Switzerland, designed to collect data across three key age groups: 6–12, 35–44, and 65–74 years. The study goal is to provide valuable insights into the oral health status of the Swiss population, helping to inform future healthcare strategies and improve patient outcomes. It aims to examine approximately 1,800 children by June 2026 and 1,650 adults by the end of 2027, across six cantons: Aargau, Bern, Lucerne, Ticino, Vaud, and Zurich.

Another key objective is to identify trends, such as the rise in early-childhood caries and establish a baseline for future public health strategies. By incorporating dental and gingival scans alongside clinical examinations, the study seeks to enhance diagnostic accuracy and explore the potential for trained dental assistants to support dental screenings. These intraoral scans, along with longitudinal follow-ups, are expected to contribute to a deeper understanding of oral health's impact on overall well-being, helping to shape more effective preventive care and public health programs.

As part of this collaboration, Align is providing its state-of-the-art iTero Lumina™ intraoral scanner, which will have a central role in the study’s data collection. The iTero Lumina scanner is designed to simplify the capture of challenging areas like the palate, edentulous spaces, partially erupted teeth and crowded teeth. Powered by iTero Multi-Direct Capture™ technology, the iTero Lumina scanner sets a new standard in digital scanning with its wider field of view 1 , large capture distance 2 , multi-angle capture 3 and superior clinical accuracy 4 . It delivers faster and more comfortable 5 scanning experience that enables highly efficient workflows while helping doctors provide an elevated patient experience.

iTero Lumina integrates near-infrared imaging (NIRI) technology, which scans the internal structure of a tooth (enamel and dentine) in real time 6 and aids in the detection and monitoring of interproximal caries lesions above the gingiva without using harmful radiation 6 . Also available on the iTero Lumina scanner is the Align™ Oral Health Suite, a digital interface that enables comprehensive oral health assessments from a single scan. It can help doctors explain oral health conditions clearly and effectively using patient-friendly language. The Align Oral Health Suite integrates advance diagnostic and visualization tools – including iTero NIRI, Occlusogram, TimeLapse, and Invisalign Outcome Simulator Pro- into one streamlined platform, allowing doctors to create and share personalized oral health reports that cover a wide range of dental conditions.

An Align-branded mobile dental van equipped with an iTero Lumina scanner will be traveling daily to schools and communities across Switzerland, enabling researchers to conduct on-site examinations and digital scans. The van is designed to operate autonomously for a full workday and equipped with dual examination chairs for efficient screening.

“We are honored to support this pioneering oral health initiative with the University of Bern and look forward to how integration of the iTero Lumina scanner into the study can enhance data quality and support the long-term goal of validating digital diagnostics as a complement to clinical examinations,” said Simon Beard, Align Technology executive vice president and managing director, EMEA. “The First Swiss Oral Health Study exemplifies the power of collaboration between academia and industry to drive meaningful innovation. The iTero Lumina scanner is helping researchers collect high-quality data efficiently, and we’re proud to see our technology contributing to better oral health outcomes for future generations.”

"This study represents a major step forward in understanding the oral health of the Swiss population. The support from Align Technology and the use of the iTero Lumina scanner have significantly enhanced our ability to collect high-quality data efficiently and comfortably for participants of all ages, including young children," said Prof. Dr. Meyer-Lückel.

1 The iTero Lumina™ intraoral scanner offers 3x larger field of view designed for more surface area capture enabling faster scanning.*Compared to the field of view of the iTero Element™ 5D imaging system, when the iTero Lumina™ intraoral scanner’s scanning distance is 12 mm.
2 The iTero Lumina™ intraoral scanner boasts a 25 mm capture distance.
3 The iTero Lumina™ intraoral scanner offers simultaneous multi-angle capture designed for less maneuvering.
4 The iTero Lumina™ intraoral scanner has scientifically proven greater accuracy* for your clinical orthodontic needs.
5 For doctors and their staff: Over other iTero™ scanners in their respective clinics . Based on a survey in September 2023 of n=22 users who participated in a global limited market release, working with iTero Lumina™ intraoral scanner for an average period of 6 months, representing both Invisalign® trained general practitioners, orthodontists, and their staff in NA, EMEA and APAC, who were presented with a 4 point level of agreement scale from strongly agree to strongly disagree with the following statement: “I prefer the iTero Lumina™ intraoral scanner over other iTero scanners in my clinic due to the comfortable scanning experience it provides. For patients: Compared to iTero Element™ 5D imaging system wand.
6 Data on file at Align Technology, as of December 4, 2018.

*Compared to the accuracy of the iTero Element™ 5D imaging system.

About Align Technology, Inc.

Align Technology designs and manufactures the Invisalign ® System, the most advanced clear aligner system in the world, iTero™ intraoral scanners and services, and exocad™ CAD/CAM software. These technology building blocks enable enhanced digital orthodontic and restorative workflows to improve patient outcomes and practice efficiencies for over 291 thousand doctor customers and are key to accessing Align’s 600 million consumer market opportunity worldwide. Over the past 28 years, Align has helped doctors treat over 21.4 million patients with the Invisalign System and is driving the evolution in digital dentistry through the Align™ Digital Platform, our integrated suite of unique, proprietary technologies and services delivered as a seamless, end-to-end solution for patients and consumers, orthodontists and GP dentists, and lab/partners. Visit www.aligntech.com for more information.

For additional information about the Invisalign system or to find an Invisalign doctor in your area, please visit www.invisalign.com . For additional information about the iTero digital scanning system, please visit www.itero.com . For additional information about exocad dental CAD/CAM offerings and a list of exocad reseller partners, please visit www.exocad.com .

Invisalign, iTero, exocad, Align, Align Digital Platform and iTero Lumina are trademarks of Align Technology, Inc.

View source version on businesswire.com: https://www.businesswire.com/news/home/20260202763390/en/

Align Technology
Madelyn Valente
(909) 833-5839
mvalente@aligntech.com

Zeno Group
Sarah Karlson
(828) 551-4201
sarah.karlson@zenogroup.com

FAQ**

How does Align Technology Inc. ALGN plan to leverage the iTero Lumina™ intraoral scanner's capabilities to improve the quality of data collection in the Swiss Oral Health Study?

Align Technology Inc. plans to utilize the iTero Lumina™ intraoral scanner to enhance the Swiss Oral Health Study by improving data collection accuracy and efficiency through advanced imaging technology, facilitating better insights into oral health outcomes.

In what ways might the collaboration between Align Technology Inc. ALGN and the University of Bern influence future public health strategies in Switzerland?

The collaboration between Align Technology Inc. and the University of Bern could enhance public health strategies in Switzerland by integrating advanced dental technologies and research into preventive care and improved orthodontic treatments, thereby promoting overall oral health.

What are the expected long-term outcomes of incorporating iTero Lumina™ scanning technology into the Swiss Oral Health Study conducted by Align Technology Inc. ALGN?

The incorporation of iTero Lumina™ scanning technology into the Swiss Oral Health Study is expected to enhance diagnostic accuracy, improve patient outcomes through precise treatment planning, and provide valuable data on the long-term efficacy of orthodontic interventions.

How does the use of data from the iTero Lumina™ scanner in this study further Align Technology Inc. ALGN's position in the field of digital orthodontics and preventive care?

The use of data from the iTero Lumina™ scanner enhances Align Technology Inc. (ALGN)'s position in digital orthodontics and preventive care by providing precise 3D impressions that improve treatment planning, patient outcomes, and overall operational efficiency.

**MWN-AI FAQ is based on asking OpenAI questions about Align Technology Inc. (NASDAQ: ALGN).

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